Rabbit Recombinant Monoclonal RAB5A antibody. Early Endosome marker. Suitable for IHC-P, WB and reacts with Rat, Human, Mouse samples. Cited in 16 publications.
Images
![Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (AB109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--western-blot-img51634.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (AB109534)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (AB109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img102889.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (AB109534)")
![Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (AB109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--western-blot-img159778.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (AB109534)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (AB109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img17581.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (AB109534)")
![Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (AB109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--western-blot-img151663.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (AB109534)")
Publications
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- Nature materials 22:644-6552022Tissue fluidification promotes a cGAS-STING cytosolic DNA response in invasive breast cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesEmanuela Frittoli,Andrea Palamidessi,Fabio Iannelli,Federica Zanardi,Stefano Villa,Leonardo Barzaghi,Hind Abdo,Valeria Cancila,Galina V Beznoussenko,Giulia Della Chiara,Massimiliano Pagani,Chiara Malinverno,Dipanjan Bhattacharya,Federica Pisati,Weimiao Yu,Viviana Galimberti,Giuseppina Bonizzi,Emanuele Martini,Alexander A Mironov,Ubaldo Gioia,Flora Ascione,Qingsen Li,Kristina Havas,Serena Magni,Zeno Lavagnino,Fabrizio Andrea Pennacchio,Paolo Maiuri,Silvia Caponi,Maurizio Mattarelli,Sabata Martino,Fabrizio d'Adda di Fagagna,Chiara Rossi,Marco Lucioni,Richard Tancredi,Paolo Pedrazzoli,Andrea Vecchione,Cristiano Petrini,Francesco Ferrari,Chiara Lanzuolo,Giovanni Bertalot,Guilherme Nader,Marco Foiani,Matthieu Piel,Roberto Cerbino,Fabio Giavazzi,Claudio Tripodo,Giorgio ScitaPubMed 36581770
- Cell reports. Medicine 3:1007402022A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency.Applications:Unspecified applicationReactive species:Unspecified reactive speciesOlav M Andersen,Nikolaj Bøgh,Anne M Landau,Gro G Pløen,Anne Mette G Jensen,Giulia Monti,Benedicte P Ulhøi,Jens R Nyengaard,Kirsten R Jacobsen,Margarita M Jørgensen,Ida E Holm,Marianne L Kristensen,Aage Kristian O Alstrup,Esben S S Hansen,Charlotte E Teunissen,Laura Breidenbach,Mathias Droescher,Ying Liu,Hanne S Pedersen,Henrik Callesen,Yonglun Luo,Lars Bolund,David J Brooks,Christoffer Laustsen,Scott A Small,Lars F Mikkelsen,Charlotte B SørensenPubMed 36099918
- Frontiers in medicine 9:8107612022Exosome Mediated Cytosolic Cisplatin Delivery Through Clathrin-Independent Endocytosis and Enhanced Anti-cancer Effect Avoiding Endosome Trapping in Cisplatin-Resistant Ovarian Cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGuannan Zhou,Yuanyuan Gu,Zhongyi Zhu,Hongdao Zhang,Wei Liu,Beiying Xu,Fangyue Zhou,Menglei Zhang,Keqin Hua,Ligang Wu,Jingxin DingPubMed 35592860
- Molecular metabolism 54:1013352021High fat / high cholesterol diet does not provoke atherosclerosis in the ω3-and ω6-polyunsaturated fatty acid synthesis-inactivated Δ6-fatty acid desaturase-deficient mouse.Applications:Unspecified applicationReactive species:Unspecified reactive speciesWilhelm Stoffel,Erika Binczek,Inga Schmidt-Soltau,Susanne Brodesser,Ina WegnerPubMed 34530175
- Molecular neurodegeneration 16:452021Accumulation of saposin in dystrophic neurites is linked to impaired lysosomal functions in Alzheimer's disease brains.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMd Golam Sharoar,Sarah Palko,Yingying Ge,Takaomi C Saido,Riqiang YanPubMed 34215298
- Nature immunology 22:312-3212021IRGM1 links mitochondrial quality control to autoimmunity.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPrashant Rai,Kyathanahalli S Janardhan,Julie Meacham,Jennifer H Madenspacher,Wan-Chi Lin,Peer W F Karmaus,Jennifer Martinez,Quan-Zhen Li,Mei Yan,Jialiu Zeng,Mark W Grinstaff,Orian S Shirihai,Gregory A Taylor,Michael B FesslerPubMed 33510463
- Cell reports 33:1084202020Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAnna Pensalfini,Seonil Kim,Shivakumar Subbanna,Cynthia Bleiwas,Chris N Goulbourne,Philip H Stavrides,Ying Jiang,Ju-Hyun Lee,Sandipkumar Darji,Monika Pawlik,Chunfeng Huo,James Peddy,Martin J Berg,John F Smiley,Balapal S Basavarajappa,Ralph A NixonPubMed 33238112
- The Journal of biological chemistry 295:8005-80162020The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of α-synuclein.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRachel Underwood et. al.PubMed 32350025
- Neurobiology of disease 134:1046262019LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease.Applications:Unspecified applicationReactive species:Unspecified reactive speciesEmily M Rocha,Briana R De Miranda,Sandra Castro,Robert Drolet,Nathan G Hatcher,Lihang Yao,Sean M Smith,Matthew T Keeney,Roberto Di Maio,Julia Kofler,Teresa G Hastings,J Timothy GreenamyrePubMed 31618685
- Nature materials 18:1252-12632019Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAndrea Palamidessi et. al.PubMed 31332337
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| IHC-P | IP | Flow Cyt | WB | ICC/IF | |
|---|---|---|---|---|---|
| Human | Tested | Not recommended | Not recommended | Tested | Not recommended |
| Mouse | Expected | Not recommended | Not recommended | Tested | Not recommended |
| Rat | Tested | Not recommended | Not recommended | Tested | Not recommended |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info 1/100 - 1/250 | Notes Perform heat-mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol. |
Species Human | Dilution info 1/100 - 1/250 | Notes Perform heat-mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol. |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info Use at an assay dependent concentration. | Notes - |
IP
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat, Human | Dilution info - | Notes - |
Flow Cyt
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info - | Notes ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
Species Rat | Dilution info - | Notes ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
Species Human | Dilution info - | Notes ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info 1/1000 - 1/10000 | Notes - |
Species Mouse | Dilution info 1/1000 - 1/10000 | Notes - |
Species Human | Dilution info 1/1000 - 1/10000 | Notes - |
ICC/IF
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Human, Rat | Dilution info - | Notes - |
Associated Products
Select an associated product type
6 products for Alternative Product
Target data
Function
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:15378032, PubMed:16410077). Contributes to the regulation of filopodia extension (PubMed:14978216). Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (PubMed:22660413). Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3 (By similarity).
Alternative names
RAB5, RAB5A, Ras-related protein Rab-5A
Recommended products
Rabbit Recombinant Monoclonal RAB5A antibody. Early Endosome marker. Suitable for IHC-P, WB and reacts with Rat, Human, Mouse samples. Cited in 16 publications.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Clone number
- EPR5438
- Purification technique
- Affinity purification Protein A
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Stable for 12 months at -20°C
Notes
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
Rab5 also known as Ras-related protein Rab-5A is a small GTPase of approximately 24 kDa. It is part of the Rab family of proteins and functions as an endosomal marker in cells. Rab5 is ubiquitously expressed but shows enriched expression in tissues with a high rate of endocytosis like the brain and liver. This protein plays a significant role in early endosome fusion and trafficking acting as an essential regulator of vesicular transport processes within the cell.
- Biological function summary
Rab5 regulates the early endocytic pathway by mediating vesicle docking and fusion processes. It is not a part of a large complex but interacts with a range of effector proteins that facilitate endosome maturation. Rab5's role as an endosomal marker makes it important for membrane trafficking receptor recycling and signal transduction. Researchers often identify Rab5 in cellular studies using endosome staining techniques or specific antibodies like Drosophila antibodies to visualize its function and distribution.
- Pathways
The endocytic network heavily involves Rab5 particularly influencing the endocytosis and endosomal signaling pathways. It frequently interacts with proteins such as EEA1 (Early Endosome Antigen 1) and Rabaptin-5 which are critical for endosomal membrane fusion. This mechanistic involvement ensures the correct transfer and processing of endocytic vesicles facilitating the continual cycle of membrane and receptor turnover in cells.
- Associated diseases and disorders
Rab5 dysfunction associates with neurological conditions such as Alzheimer's disease and cancer. Alterations in Rab5 levels or function can disrupt normal endosomal trafficking leading to amyloid beta peptide accumulation in Alzheimer's. Additionally Rab5's role in cancer relates to its regulation of growth factor receptors where its interaction with proteins like the PE marker influences tumor progression. Understanding Rab5 pathways and interactions paves the way for developing targeted therapeutics in these disorders.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
8 product images
![Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--western-blot-img51634.jpg "Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)")
Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)
Lane 1: Wild type HAP1 whole cell lysate (20 μg)
Lane 2: Rab5 knockout HAP1 whole cell lysate (20 μg)
Lane 3: Hu brain whole cell lysate (20 μg)
Lane 4: Ms brain whole cell lysate (20 μg)
Lanes 1 - 4: Merged signal (red and green). Green - ab109534 observed at 25 kDa. Red - loading control, Anti-GAPDH antibody [6C5] - Loading Control ab8245, observed at 37 kDa.All lanes: Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)
Predicted band size: 24 kDa
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img102889.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)
Immunohistochemical staining of paraffin embedded human pancreas with purified ab109534 at a working dilution of 1 in 1000. The secondary antibody used is a HRP polymer for rabbit IgG. The sample is counter-stained with hematoxylin. Antigen retrieval was perfomed using Tris-EDTA buffer, pH 9.0. PBS was used instead of the primary antibody as the negative control, and is shown in the inset.
![Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--western-blot-img159778.jpg "Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)")
Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)
Blocking buffer: 5% NFDM/TBST
Dilution buffer: 5% NFDM/TBST
All lanes: Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534) at 1/5000 dilution
Lane 1: Mouse brain at 10 µg
Lane 2: Rat brain at 10 µg
SecondaryAll lanes: HRP goat anti-rabbit (H+L) at 1/1000 dilution
Predicted band size: 24 kDa
Observed band size: 24 kDa
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img17581.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)")
This image is courtesy of an anonymous customer review.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Pancreas tissue sections (with ADM and PanIN lesions) from KC mice labeling Rab5 with ab109534 at 1/200 dilution. Tissue was fixed with paraformaldehyde and permeabilized with TritonX100 0.1% for 10 min at room temperature. Heat-mediated antigen retrieval was performed using TRIS-EDTA pH9 buffer. Tissue sections were blocked with 10% goat serum for 1 hour at 20°C. A polyclonal goat anti-rabbit Alexa Fluor 488 secondary antibody was used at 1/500 dilution.
![Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--western-blot-img151663.jpg "Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)")
Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)
Blocking buffer: 5% NFDM/TBST
Dilution buffer: 5% NFDM/TBST
All lanes: Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534) at 1/5000 dilution
Lane 1: MCF7 cell lysate at 10 µg
Lane 2: HEK293 cell lysate at 10 µg
SecondaryAll lanes: HRP goat anti-rabbit (H+L) at 1/1000 dilution
Predicted band size: 24 kDa
Observed band size: 24 kDa
![Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--western-blot-img70501.jpg "Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)")
Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)
All lanes: Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534) at 1/1000 dilution
Lane 1: 293T cell lysate at 10 µg
Lane 2: HeLa cell lysate at 10 µg
Lane 3: Jurkat cell lysate at 10 µg
Predicted band size: 24 kDa
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img72277.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)
Immunohistochemical staining of Rab5 in paraffin embedded human brain tissue with unpurified ab109534, at 1/100 dilution.
Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
![Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--western-blot-img429977.jpg "Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)")
Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)
ab109534 was shown to react with RAB5A in wild-type HAP1 cells in Western blot with loss of signal observed in a RAB5A knockout cell line. Wild-type HAP1 and RAB5A knockout cell lysates were subjected to SDS-PAGE. Membranes were blocked in 5% milk in TBST for 1 hr before incubation with ab109534 overnight at 4 °C at a 1000 dilution. Blots were incubated with secondary antibodies at 0.2ug/mL before imaging.
These data were provided by YCharOS Inc., an open science company with the mission of characterizing commercially available antibody reagents for all human proteins. Abcam and YCharOS are working together to help address the reproducibility crisis by enabling the life science community to better evaluate commercially available antibodies.
All lanes: Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534) at 1/1000 dilution
Lane 1: Wild-type HAP1 lysate at 20 µg
Lane 2: RAB5A Knockout HAP1 lysate at 20 µg
Observed band size: 24 kDa
![Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--western-blot-img70501.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img72277.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)")
![Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534), expandable thumbnail](https://content.abcam.com/products/images/rab5-antibody-epr5438-early-endosome-marker-ab109534--western-blot-img429977.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Rab5 antibody [EPR5438] - Early Endosome Marker (ab109534)")
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