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AB37415

Rabbit IgG, polyclonal - Isotype Control

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(405 Publications)

Rabbit IgG, polyclonal - Isotype Control (ab37415) is a rabbit polyclonal antibody used in Flow Cytometry, IP, IHC-P, ICC/IF, ELISA, ChIP/Chip.

- Over 270 publications
- Trusted since 2006
3 Images
Flow Cytometry - Rabbit IgG, polyclonal - Isotype Control (AB37415)
  • Flow Cyt

PubMed

Flow Cytometry - Rabbit IgG, polyclonal - Isotype Control (AB37415)

Histogram showing the fluorescence signal for ADRB2-FITC in PBMCs compared to an Isotype control.

PBMCs were generated from freshly-drawn blood from healthy human donors. After staining with antibodies against ADRB2 (ab36956) or an isotype control (ab37415), cells were incubated with FITC-labeled secondary anti-rabbit-IgG antibody, and ADRB2 expression was assessed by flow cytometry.

Image from Hilbert T et al., PLoS One. 2013;8(5):e65024. Fig 3(A).; doi: 10.1371/journal.pone.0065024. Reproduced under the Creative Commons license http://creativecommons.org/licenses/by/4.0/

Flow Cytometry - Rabbit IgG, polyclonal - Isotype Control (AB37415)
  • Flow Cyt

Supplier Data

Flow Cytometry - Rabbit IgG, polyclonal - Isotype Control (AB37415)

Flow cytometric overlay histogram showing Jurkat (Human T Cell leukemia cell line), was stained with Rabbit IgG, polyclonal - Isotype Control (ab37415) and Rabbit Anti-Human DR5-UNLB followed by Mouse Anti-Rabbit IgG-PE.

ChIP - Rabbit IgG, polyclonal - Isotype Control (AB37415)
  • ChIP

PubMed

ChIP - Rabbit IgG, polyclonal - Isotype Control (AB37415)

ChIP-qPCR for H3K36me2 on the BTF3 locus in NTKO and TKO cells. Methylation enrichment was tested 5 kb upstream of the TSS (5′) and at the TSS (right). ab37415 was used as the isotype contol.

Image from Popovic R et al., PLoS Genet.. 2014;10(9):e1004566. Fig 1(E).; doi: 10.1371/journal.pgen.1004566. Reproduced under the Creative Commons license http://creativecommons.org/licenses/by/4.0/

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Applications

ICC/IF, ELISA, Flow Cyt, ChIP/Chip, IHC-P

applications

Specificity

This antibody has been selected to be an isotype control as it has no known specificity. Please note that the rabbit IgG Fc region may bind nonspecifically to human tissue. Rabbit IgG is an isotype control used to estimate the non-specific binding of target primary antibodies due to Fc binding or other protein-protein interactions.

Reactivity data

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Product details

Rabbit IgG, polyclonal - Isotype Control (ab37415) is validated for use in ChIP/Chip, ELISA, Flow Cyt, ICC/IF, IHC-P.

Rabbit IgG, polyclonal - Isotype Control (ab37415) has been cited over 279 times in peer reviewed journals and is trusted by the scientific community.

Abcam's high quality validation processes ensure Rabbit IgG, polyclonal - Isotype Control (ab37415) has high sensitivity and specificity. Rabbit IgG Isotype Control (ab37415) is sold in 5 mg selling sizes.

REACH authorisation
Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances.
It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.

Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Purification notes
Protein A-purified
Storage buffer
pH: 8.2 Constituents: 100% Borate buffered saline
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Publications (405)

Recent publications for all applications. Explore the full list and refine your search

PLoS genetics 21:e1011895 PubMed41066503

2025

Convergent evolution of H4K16ac-mediated dosage compensation in the ZW species Artemia franciscana.

Applications

Unspecified application

Species

Unspecified reactive species

Frederic Zimmer,Annika Maria Fox,Qiaowei Pan,Frank Rühle,Peter Andersen,Ann-Kathrin Huylmans,Tanja Schwander,M Felicia Basilicata,Claudia Isabelle Keller Valsecchi

Nature communications 16:8647 PubMed41028752

2025

Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4.

Applications

Unspecified application

Species

Unspecified reactive species

Burak Ozkan,Mitzy Rios de Anda,Elisa Hall-Ponsele,Maria Rosa Portero Migueles,Amani Alshaikh,Marta Hanzevacki,Moriyah Naama,Katharine Furlong,Gareth A Roberts,Meryam Beniazza,My Linh Huynh,Michael R O'Dwyer,Sonia Yiakoumi,Christos Spanos,Hazar Yassen,Keisuke Kaji,Hitoshi Niwa,Yosef Buganim,Sally Lowell,Abdenour Soufi

Arthritis research & therapy 27:172 PubMed40877928

2025

Regulation of fibroblast-like synoviocyte function by cadherin 6 in rheumatoid arthritis.

Applications

Unspecified application

Species

Unspecified reactive species

Camilla R L Machado,Eunice Choi,Narayanan B Perumal,Robert J Benschop,Gregory R Dressler,Wei Wang,David L Boyle,Gary S Firestein

Cell reports 44:116025 PubMed40700020

2025

IGSF10 is a RET antagonist regulating Ewing sarcoma growth and GnRH neuron migration.

Applications

Unspecified application

Species

Unspecified reactive species

Panneerselvam Jayabal,Xiuye Ma,Maleeha Akram,Hannah Bow,Pranay Mandal,Naira Mansano,Yidong Chen,Susan T Weintraub,Peter J Houghton,Susan Wray,Yuzuru Shiio

Frontiers in immunology 16:1582526 PubMed40655144

2025

Neutrophils aggravate inflammatory lesions in intestinal organoids from necrotizing enterocolitis.

Applications

Unspecified application

Species

Unspecified reactive species

Kim M Heuer,Michael Boettcher,Laia Pagerols Raluy,Johanna Hagens,Jan P Kolman,Madeleine J Bunders,Jasmin Wesche,Jasmin Knopf,Martin Herrmann,Konrad Reinshagen,Deirdre Vincent

Journal of cellular and molecular medicine 29:e70682 PubMed40638555

2025

XML Attenuates Ox-LDL-Induced Endothelial Progenitor Cell Senescence via Gria2 and cAMP Pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Jinjian Wu,Guotao Lu,Zhou Luo,Meng Cai,Qiankun He,Jie Su,Jianfeng Liu,Rong Wang,Chunyan Kuang

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 39:e70594 PubMed40354028

2025

The RNA-Binding Proteins MCPIP2 and IGF2BP1 Competitively Modulate Breast Tumor Angiogenesis by Antagonizing VEGFA mRNA Stability and Expression.

Applications

Unspecified application

Species

Unspecified reactive species

Wenbao Lu,Hongwei Li,Xueting Liu,Ailing Li,Ruijuan Xiu

Frontiers in immunology 16:1565252 PubMed40342425

2025

High-mobility group protein B1 derived mutant peptide mB Box-97 inhibits the formation of neutrophil extracellular traps.

Applications

Unspecified application

Species

Unspecified reactive species

Kunal R More,Aishwarya Devaraj,Frank H Robledo-Avila,Santiago Partida-Sanchez,Lauren O Bakaletz,Steven D Goodman

The Journal of cell biology 224: PubMed40304687

2025

Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin.

Applications

Unspecified application

Species

Unspecified reactive species

Tatsuki Isogai,Koichiro M Hirosawa,Miki Kanno,Ayano Sho,Rinshi S Kasai,Naoko Komura,Hiromune Ando,Keiko Furukawa,Yuhsuke Ohmi,Koichi Furukawa,Yasunari Yokota,Kenichi G N Suzuki

Biomedicines 13: PubMed40299521

2025

Inulin Diet Alleviates Abdominal Aortic Aneurysm by Increasing Akkermansia and Improving Intestinal Barrier.

Applications

Unspecified application

Species

Unspecified reactive species

Shuang Guo,Fen Yang,Jiyu Zhang,Yuhan Liao,Ni Xia,Tingting Tang,Chaolong Wang,Qing K Wang,Chen Chen,Desheng Hu,Zhilei Shan,Xiang Cheng
View all publications

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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