Rabbit monoclonal, [MOPC-21] Isotype Control
IgG
Rabbit
Preservative: 0.02% Proclin 300
Constituents: 99% PBS
Liquid
Monoclonal
Select an associated product type
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Immunoglobulin heavy constant gamma 4, Ig gamma-4 chain C region, IGHG4
Rabbit monoclonal, [MOPC-21] Isotype Control
IgG
Rabbit
Preservative: 0.02% Proclin 300
Constituents: 99% PBS
Liquid
Monoclonal
MOPC-21
Affinity purification Protein A
kappa
Blue Ice
1-2 weeks
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
ab242443 has unknown specificity and may be used as a negative control.
We have tested this species and application combination and it works. It is covered by our product promise.
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This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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