AB200369

Anti-RANK antibody

Name: Anti-RANK antibody (ab200369) | Abcam
Brand: Abcam Limited
SKU: AB200369
Price: 535 USD
Availability: InStock

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(17 Publications)

Rabbit Polyclonal RANK antibody. Suitable for WB and reacts with Mouse, Human samples. Cited in 17 publications. Immunogen corresponding to Synthetic Peptide within Human TNFRSF11A.

View Alternative Names

CD265, RANK, TNFRSF11A, Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor, Receptor activator of NF-KB, ODFR

1 Images

Supplier Data

Western blot - Anti-RANK antibody (AB200369)

Gel : 8% SDS-PAGE

All lanes:

Western blot - Anti-RANK antibody (ab200369) at 1/200 dilution

Lane 1:

Human liver tissue lysate at 40 µg

Lane 2:

Mouse kidney tissue lysate at 40 µg

Predicted band size: 66 kDa

false

Exposure time: 1min

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Human

Applications

applications

Immunogen

Synthetic Peptide within Human TNFRSF11A. The exact immunogen used to generate this antibody is proprietary information.

Q9Y6Q6

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/200 - 1/1000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/200 - 1/1000", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed : 9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity).

See full target information TNFRSF11A

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Publications (17)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 15:7324 PubMed39183203

2024

Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathy.

Applications

Unspecified application

Species

Unspecified reactive species

Mengyu Liao,Xu Zhu,Yumei Lu,Xiaoping Yi,Youhui Hu,Yumeng Zhao,Zhisheng Ye,Xu Guo,Minghui Liang,Xin Jin,Hong Zhang,Xiaohong Wang,Ziming Zhao,Yupeng Chen,Hua Yan

iScience 26:107749 PubMed37701568

2023

Immunoglobulin G inhibits glucocorticoid-induced osteoporosis through occupation of FcγRI.

Applications

Unspecified application

Species

Unspecified reactive species

Lijuan Jiang,Wenlin Qiu,Xuefei Wang,Xiaoru Duan,Xiaoxiao Han,Tong Yu,Shenghui Wen,Zhijun Luo,Ruizhi Feng,Yao Teng,Haifeng Yin,Christian M Hedrich,Guo-Min Deng

Journal of molecular medicine (Berlin, Germany) 101:607-620 PubMed37121919

2023

SOST gene suppression stimulates osteocyte Wnt/β-catenin signaling to prevent bone resorption and attenuates particle-induced osteolysis.

Applications

Unspecified application

Species

Unspecified reactive species

Zixue Jiao,Hao Chai,Shendong Wang,Chunguang Sun,Qun Huang,Wei Xu

Life (Basel, Switzerland) 13: PubMed36836664

2023

Secukinumab and Black Garlic Downregulate OPG/RANK/RANKL Axis and Devitalize Myocardial Interstitial Fibrosis Induced by Sunitinib in Experimental Rats.

Applications

Unspecified application

Species

Unspecified reactive species

Hoda E Mohamad,Mervat E Asker,Mohamed A Shaheen,Nourhan M Baraka,Omer I Fantoukh,Abdulaziz Alqahtani,Alaa E Salama,Yasmin K Mahmoud

BioMed research international 2022:7740079 PubMed35463988

2022

RANKL Impairs the TLR4 Pathway by Increasing TRAF6 and RANK Interaction in Macrophages.

Applications

Unspecified application

Species

Unspecified reactive species

Ryerson Fonseca Mota,Paulo Henrique Cavalcanti de Araújo,Maria Eduarda Ramos Cezine,Flávia Sayuri Matsuo,Rodrigo Jair Morandi Metzner,Carlos Alberto Oliveira de Biagi Junior,Kamila Chagas Peronni,Hiroki Hayashi,Munehisa Shimamura,Hironori Nakagami,Mariana Kiomy Osako

Journal of healthcare engineering 2022:9364467 PubMed35190765

2022

lncRNA FGD5-AS1 Regulates Bone Marrow Stem Cell Proliferation and Apoptosis by Affecting miR-296-5p/STAT3 Axis in Steroid-Induced Osteonecrosis of the Femoral Head.

Applications

Unspecified application

Species

Unspecified reactive species

Yadi Wu,Lun Fang,Yong Gao,Zhiqiu Zhao,Lu Zhou,Gang Zhang

Oncology letters 23:96 PubMed35154427

2022

Capecitabine inhibits epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells by mediating the RANK/RANKL pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Minghai Shao,Caiping Jiang,Changhui Yu,Haijian Jia,Yanli Wang,Xinli Mao

Evidence-based complementary and alternative medicine : eCAM 2021:7114139 PubMed34754319

2021

QiangGuYin Modulates the OPG/RANKL/RANK Pathway by Increasing Secretin Levels during Treatment of Primary Type I Osteoporosis.

Applications

Unspecified application

Species

Unspecified reactive species

Xuefei Li,Longkang Cui,Wenhua Chen,Yuan Fang,Gaobo Shen,Zhen Li,Bingbing Zhang,Lianguo Wu

Stem cell research & therapy 12:18 PubMed33413642

2021

LncRNA NORAD promotes bone marrow stem cell differentiation and proliferation by targeting miR-26a-5p in steroid-induced osteonecrosis of the femoral head.

Applications

Unspecified application

Species

Unspecified reactive species

Dapeng Fu,Sheng Yang,Jianmin Lu,Haoyi Lian,Kairong Qin

Journal of cellular and molecular medicine 23:6744-6754 PubMed31402549

2019

Up-regulated CST5 inhibits bone resorption and activation of osteoclasts in rat models of osteoporosis via suppression of the NF-κB pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Fei Wang,Chuanzhu Zhang,Wei Ge,Guoqiang Zhang

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-RANK antibody

Western blot - Anti-RANK antibody (AB200369)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (17)

Product promise