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AB222215

Anti-RANK antibody

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(5 Publications)

Rabbit Polyclonal RANK antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human TNFRSF11A aa 50 to C-terminus.

View Alternative Names

CD265, RANK, TNFRSF11A, Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor, Receptor activator of NF-KB, ODFR

1 Images
Immunocytochemistry/ Immunofluorescence - Anti-RANK antibody (AB222215)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-RANK antibody (AB222215)

PFA-fixed, Triton X-100 permeabilized A431 (human epidermoid carcinoma cell line) cells stained for RANK (green) using ab222215 at 4 μg/ml in ICC/IF.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human TNFRSF11A aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9Y6Q6

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed : 9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity).
See full target information TNFRSF11A
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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

eLife 14: PubMed40990917

2025

Ubiquitination-activated TAB-TAK1-IKK-NF-κB axis modulates gene expression for cell survival in the lysosomal damage response.

Applications

Unspecified application

Species

Unspecified reactive species

Akinori Endo,Chikage Takahashi,Naoko Ishibashi,Yasumasa Nishito,Koji Yamano,Keiji Tanaka,Yukiko Yoshida

Cancers 14: PubMed36358621

2022

Prognostic Value and Quantitative CT Analysis in RANKL Expression of Spinal GCTB in the Denosumab Era: A Machine Learning Approach.

Applications

Unspecified application

Species

Unspecified reactive species

Qizheng Wang,Yongye Chen,Siyuan Qin,Xiaoming Liu,Ke Liu,Peijin Xin,Weili Zhao,Huishu Yuan,Ning Lang

Scientific reports 11:24088 PubMed34916549

2021

Bioengineering the ameloblastoma tumour to study its effect on bone nodule formation.

Applications

Unspecified application

Species

Unspecified reactive species

Deniz Bakkalci,Amrita Jay,Azadeh Rezaei,Christopher A Howard,Håvard Jostein Haugen,Judith Pape,Shosei Kishida,Michiko Kishida,Gavin Jell,Timothy R Arnett,Stefano Fedele,Umber Cheema

Arthritis & rheumatology (Hoboken, N.J.) 73:1021-1032 PubMed33314777

2021

Novel Majeed Syndrome-Causing LPIN2 Mutations Link Bone Inflammation to Inflammatory M2 Macrophages and Accelerated Osteoclastogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Farzana Bhuyan,Adriana A de Jesus,Jacob Mitchell,Evgenia Leikina,Rachel VanTries,Ronit Herzog,Karen B Onel,Andrew Oler,Gina A Montealegre Sanchez,Kim A Johnson,Lena Bichell,Bernadette Marrero,Luis Fernandez De Castro,Yan Huang,Katherine R Calvo,Michael T Collins,Sundar Ganesan,Leonid V Chernomordik,Polly J Ferguson,Raphaela Goldbach-Mansky

BioMed research international 2020:2753414 PubMed32337233

2020

Effects of the Bone/Bone Marrow Microenvironments on Prostate Cancer Cells and CD59 Expression.

Applications

Unspecified application

Species

Unspecified reactive species

Bo Yan,Yan Li,Shaoju Min,Peng Zhang,Bin Xu,Zhen Wang,Wei Zhang,Jiasheng Chen,Guangheng Luo,Chunxiao Liu
View all publications
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Product promise

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