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Mouse Monoclonal RANKL antibody. Suitable for WB and reacts with Rat, Recombinant full length protein - Rat samples. Cited in 12 publications. Immunogen corresponding to Recombinant Fragment Protein within Rat Tnfsf11 aa 100-250.


Images

Western blot - Anti-RANKL antibody [C1] (AB239607), expandable thumbnail
  • Western blot - Anti-RANKL antibody [C1] (AB239607), expandable thumbnail

Publications

Key facts

Isotype
IgG2a
Host species
Mouse
Storage buffer

pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.12% PBS

Form
Liquid
Clonality
Monoclonal

Immunogen

  • Recombinant Fragment Protein within Rat Tnfsf11 aa 100-250. The exact immunogen used to generate this antibody is proprietary information. Database link Q9ESE2

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WBIHC-P
Mouse
Predicted
Not recommended
Rat
Tested
Not recommended
Recombinant full length protein - Rat
Tested
Not recommended

Tested
Tested

Species
Rat
Dilution info
0.50000-5.00000 µg/mL
Notes

-

Species
Recombinant full length protein - Rat
Dilution info
0.50000-5.00000 µg/mL
Notes

-

Predicted
Predicted

Species
Mouse
Dilution info
-
Notes

-

Not recommended
Not recommended

Species
Rat, Mouse, Recombinant full length protein - Rat
Dilution info
-
Notes

-

Associated Products

Select an associated product type

7 products for Alternative Product

Target data

Function

Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. Induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precursor cells, chief among which is induction of long lasting oscillations in the intracellular concentration of Ca (2+) resulting in the activation of NFATC1, which translocates to the nucleus and induces osteoclast-specific gene transcription to allow differentiation of osteoclasts. During osteoclast differentiation, in a TMEM64 and ATP2A2-dependent manner induces activation of CREB1 and mitochondrial ROS generation necessary for proper osteoclast generation.

Alternative names

CD254, Opgl, Rankl, Trance, Tnfsf11, Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, Osteoprotegerin ligand, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, ODF, OPGL, RANKL, TRANCE

Recommended products

Mouse Monoclonal RANKL antibody. Suitable for WB and reacts with Rat, Recombinant full length protein - Rat samples. Cited in 12 publications. Immunogen corresponding to Recombinant Fragment Protein within Rat Tnfsf11 aa 100-250.

Key facts

Isotype
IgG2a
Form
Liquid
Clonality
Monoclonal
Immunogen
  • Recombinant Fragment Protein within Rat Tnfsf11 aa 100-250. The exact immunogen used to generate this antibody is proprietary information. Database link Q9ESE2
Clone number
C1
Purification technique
Affinity purification Protein A/G
Light chain type
kappa
Concentration
Loading...
Purification notes

Purified from TCS.

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

2 product images

  • Western blot - Anti-RANKL antibody [C1] (ab239607), expandable thumbnail

    Western blot - Anti-RANKL antibody [C1] (ab239607)

    All lanes: Western blot - Anti-RANKL antibody [C1] (ab239607) at 5 µg/mL

    All lanes: Rat thymus tissue lysate

    Secondary

    All lanes: HRP-Goat Anti-Mouse IgG

    Predicted band size: 35 kDa

  • Western blot - Anti-RANKL antibody [C1] (ab239607), expandable thumbnail

    Western blot - Anti-RANKL antibody [C1] (ab239607)

    All lanes: Western blot - Anti-RANKL antibody [C1] (ab239607) at 5 µg/mL

    All lanes: Recombinant rat RANKL protein

    Predicted band size: 35 kDa

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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