AB9679

Anti-RANTES antibody

Name: Anti-RANTES antibody (ab9679) | Abcam
Brand: Abcam Limited
SKU: AB9679
Rating: 4 (8 reviews)

(8 Reviews)

(32 Publications)

Rabbit Polyclonal RANTES antibody. Suitable for sELISA and reacts with Recombinant full length protein - Human samples. Cited in 32 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human CCL5.

View Alternative Names

D17S136E, SCYA5, CCL5, C-C motif chemokine 5, EoCP, Eosinophil chemotactic cytokine, SIS-delta, Small-inducible cytokine A5, T cell-specific protein P228, T-cell-specific protein RANTES, TCP228

1 Images

Sandwich ELISA - Anti-RANTES antibody (AB9679)

sELISA

Supplier Data

Sandwich ELISA - Anti-RANTES antibody (AB9679)

ab9679 detecting RANTES by sandwich ELISA, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hRANTES.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

Unknown

Light chain type

unknown

Carrier free

Applications

sELISA

applications

Immunogen

Recombinant Full Length Protein corresponding to Human CCL5.

P13501

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Recombinant full length protein - Human": { "sELISA-species-checked": "testedAndGuaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }

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Product details

Although some customers have been successful in IHC we no longer batch test in this application.

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Properties and storage information

Form

Lyophilized

Reconstitution

Reconstitute with 200µl of sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.

Purification technique

Affinity purification Immunogen

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) (PubMed : 1380064, PubMed : 15923218, PubMed : 16791620, PubMed : 8525373, PubMed : 9516414). May also be an agonist of the G protein-coupled receptor GPR75, stimulating inositol trisphosphate production and calcium mobilization through its activation. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells (PubMed : 23979485).

See full target information CCL5

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Publications (32)

Recent publications for all applications. Explore the full list and refine your search

JCI insight 7: PubMed36301668

2022

Metastatic pancreatic neuroendocrine tumors feature elevated T cell infiltration.

Applications

Unspecified application

Species

Unspecified reactive species

Jacques Greenberg,Jessica Limberg,Akanksha Verma,David Kim,Xiang Chen,Yeon J Lee,Maureen D Moore,Timothy M Ullmann,Jessica W Thiesmeyer,Zachary Loewenstein,Kevin J Chen,Caitlin E Egan,Dessislava Stefanova,Rohan Bareja,Rasa Zarnegar,Brendan M Finnerty,Theresa Scognamiglio,Yi-Chieh Nancy Du,Olivier Elemento,Thomas J Fahey,Irene M Min

Cell death & disease 13:478 PubMed35589690

2022

Cancer associated fibroblast-derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Haixu Xu,Jie Zhao,Jinping Li,Zhifeng Zhu,Zhaohai Cui,Ran Liu,Rong Lu,Zhi Yao,Qiong Xu

Cell cycle (Georgetown, Tex.) 21:1003-1019 PubMed35192424

2022

Hsa_circ_0007059 promotes apoptosis and inflammation in cardiomyocytes during ischemia by targeting microRNA-378 and microRNA-383.

Applications

Unspecified application

Species

Unspecified reactive species

Chaorui Xu,Zhuowen Jia,Xuefei Cao,Sha Wang,Jipeng Wang,Liping An

Cancers 13: PubMed34771505

2021

An Immune-Related Gene Prognostic Index for Triple-Negative Breast Cancer Integrates Multiple Aspects of Tumor-Immune Microenvironment.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaowei Wang,Wenjia Su,Dabei Tang,Jing Jing,Jing Xiong,Yuwei Deng,Huili Liu,Wenjie Ma,Zhaoliang Liu,Qingyuan Zhang

International journal of molecular sciences 22: PubMed34298951

2021

Rapid Internalization and Nuclear Translocation of CCL5 and CXCL4 in Endothelial Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Annemiek Dickhout,Dawid M Kaczor,Alexandra C A Heinzmann,Sanne L N Brouns,Johan W M Heemskerk,Marc A M J van Zandvoort,Rory R Koenen

Journal of hepatocellular carcinoma 8:599-611 PubMed34178876

2021

Blocking the CCL5-CCR5 Axis Using Maraviroc Promotes M1 Polarization of Macrophages Cocultured with Irradiated Hepatoma Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Yuan Zhuang,Xiaomei Zhao,Baoying Yuan,Zhaochong Zeng,Yixing Chen

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 32:76-81 PubMed33893769

2021

Intrahepatic Expression of C-C Motif ligand 5 in Patients with Chronic Hepatitis B.

Applications

Unspecified application

Species

Unspecified reactive species

Xiang-An Zhao,Jian Wang,Haiyan Chang,Yong Liu,Yuxin Chen,Guangmei Chen,Rui Huang,Chao Wu

Scientific reports 10:16364 PubMed33004937

2020

Elevated adipose tissue associated IL-2 expression in obesity correlates with metabolic inflammation and insulin resistance.

Applications

Unspecified application

Species

Unspecified reactive species

Shihab Kochumon,Ashraf Al Madhoun,Fatema Al-Rashed,Reeby Thomas,Sardar Sindhu,Ebaa Al-Ozairi,Fahd Al-Mulla,Rasheed Ahmad

Cell stem cell 27:238-253.e6 PubMed32697949

2020

BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse.

Applications

Unspecified application

Species

Unspecified reactive species

Lingfei Jia,Wuchang Zhang,Cun-Yu Wang

Neoplasma 67:1063-1073 PubMed32567935

2020

CircABCB10 silencing inhibits the cell ferroptosis and apoptosis by regulating the miR-326/CCL5 axis in rectal cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Z Y Xian,B Hu,T Wang,J L Cai,J Y Zeng,Q Zou,P X Zhu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-RANTES antibody

Sandwich ELISA - Anti-RANTES antibody (AB9679)

Key facts

Host species

Clonality

Isotype

Light chain type

Carrier free

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Reconstitution

Purification technique

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Product protocols

Target data

Publications (32)

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