Rabbit Polyclonal RANTES antibody. Suitable for sELISA and reacts with Recombinant full length protein - Human samples. Cited in 30 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human CCL5.
Images
Publications
Filter by
- JCI insight 7:2022Metastatic pancreatic neuroendocrine tumors feature elevated T cell infiltration.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJacques Greenberg,Jessica Limberg,Akanksha Verma,David Kim,Xiang Chen,Yeon J Lee,Maureen D Moore,Timothy M Ullmann,Jessica W Thiesmeyer,Zachary Loewenstein,Kevin J Chen,Caitlin E Egan,Dessislava Stefanova,Rohan Bareja,Rasa Zarnegar,Brendan M Finnerty,Theresa Scognamiglio,Yi-Chieh Nancy Du,Olivier Elemento,Thomas J Fahey,Irene M MinPubMed 36301668
- Cell death & disease 13:4782022Cancer associated fibroblast-derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesHaixu Xu,Jie Zhao,Jinping Li,Zhifeng Zhu,Zhaohai Cui,Ran Liu,Rong Lu,Zhi Yao,Qiong XuPubMed 35589690
- Cancers 13:2021An Immune-Related Gene Prognostic Index for Triple-Negative Breast Cancer Integrates Multiple Aspects of Tumor-Immune Microenvironment.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXiaowei Wang,Wenjia Su,Dabei Tang,Jing Jing,Jing Xiong,Yuwei Deng,Huili Liu,Wenjie Ma,Zhaoliang Liu,Qingyuan ZhangPubMed 34771505
- International journal of molecular sciences 22:2021Rapid Internalization and Nuclear Translocation of CCL5 and CXCL4 in Endothelial Cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAnnemiek Dickhout,Dawid M Kaczor,Alexandra C A Heinzmann,Sanne L N Brouns,Johan W M Heemskerk,Marc A M J van Zandvoort,Rory R KoenenPubMed 34298951
- Journal of hepatocellular carcinoma 8:599-6112021Blocking the CCL5-CCR5 Axis Using Maraviroc Promotes M1 Polarization of Macrophages Cocultured with Irradiated Hepatoma Cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYuan Zhuang,Xiaomei Zhao,Baoying Yuan,Zhaochong Zeng,Yixing ChenPubMed 34178876
- The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 32:76-812021Intrahepatic Expression of C-C Motif ligand 5 in Patients with Chronic Hepatitis B.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXiang-An Zhao,Jian Wang,Haiyan Chang,Yong Liu,Yuxin Chen,Guangmei Chen,Rui Huang,Chao WuPubMed 33893769
- Scientific reports 10:163642020Elevated adipose tissue associated IL-2 expression in obesity correlates with metabolic inflammation and insulin resistance.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShihab Kochumon et. al.PubMed 33004937
- Cell stem cell 27:238-253.e62020BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLingfei Jia et. al.PubMed 32697949
- Neoplasma 67:1063-10732020CircABCB10 silencing inhibits the cell ferroptosis and apoptosis by regulating the miR-326/CCL5 axis in rectal cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZ Y Xian et. al.PubMed 32567935
- Cancer science 111:209-2182019Significant association between high serum CCL5 levels and better disease-free survival of patients with early breast cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYukie Fujimoto,Natsuko Inoue,Koji Morimoto,Takahiro Watanabe,Seiichi Hirota,Michiko Imamura,Yosuke Matsushita,Toyomasa Katagiri,Haruki Okamura,Yasuo MiyoshiPubMed 31724785
Key facts
- Isotype
- Unknown
- Host species
- Rabbit
- Storage buffer
- Standard buffer
- Form
- Lyophilized
- Clonality
- Polyclonal
Immunogen
- Recombinant Full Length Protein corresponding to Human CCL5. Database link P13501
Reactivity data
Select an application| sELISA | |
|---|---|
| Recombinant full length protein - Human | Tested |
sELISA
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Recombinant full length protein - Human | Dilution info - | Notes - |
Associated Products
Select an associated product type
3 products for Alternative Product
Target data
Function
Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) (PubMed:1380064, PubMed:15923218, PubMed:16791620, PubMed:8525373, PubMed:9516414). May also be an agonist of the G protein-coupled receptor GPR75, stimulating inositol trisphosphate production and calcium mobilization through its activation. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells (PubMed:23979485).
Alternative names
D17S136E, SCYA5, CCL5, C-C motif chemokine 5, EoCP, Eosinophil chemotactic cytokine, SIS-delta, Small-inducible cytokine A5, T cell-specific protein P228, T-cell-specific protein RANTES, TCP228
Recommended products
Rabbit Polyclonal RANTES antibody. Suitable for sELISA and reacts with Recombinant full length protein - Human samples. Cited in 30 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human CCL5.
Key facts
- Isotype
- Unknown
- Host species
- Rabbit
- Storage buffer
- Standard buffer
- Form
- Lyophilized
- Clonality
- Polyclonal
- Immunogen
- Recombinant Full Length Protein corresponding to Human CCL5. Database link P13501
- Purification technique
- Affinity purification Immunogen
- Light chain type
- unknown
- Reconstitution
- Reconstitute with 200µl of sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
Notes
Although some customers have been successful in IHC we no longer batch test in this application.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
Sandwich ELISA - Anti-RANTES antibody (ab9679)
ab9679 detecting RANTES by sandwich ELISA, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hRANTES.
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com