JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB197673

Anti-RAP1A antibody

Be the first to review this product! Submit a review

|

(4 Publications)

Rabbit Polyclonal RAP1A antibody. Suitable for IHC-P and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Fusion protein corresponding to RAP1A, fused to RAP1A.

View Alternative Names

KREV1, RAP1A, Ras-related protein Rap-1A, C21KG, G-22K, GTP-binding protein smg p21A, Ras-related protein Krev-1

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAP1A antibody (AB197673)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAP1A antibody (AB197673)

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling RAP1A with ab197673 at 1/35 dilution.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAP1A antibody (AB197673)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAP1A antibody (AB197673)

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling RAP1A with ab197673 at 1/35 dilution.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Fusion protein corresponding to RAP1A, fused to RAP1A. The exact immunogen used to generate this antibody is proprietary information.

P62834

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/25 - 1/100", "IHCP-species-notes": "<p></p>" }, "Cow": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes (PubMed : 17916086). Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. Facilitates the progressive accumulation of CDH1 at mature desmosome junctions via cAMP-dependent signaling and its interaction with PKP3 (PubMed : 25208567). May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions.
See full target information RAP1A
style
left-column

Publications (4)

Recent publications for all applications. Explore the full list and refine your search

PloS one 20:e0328263 PubMed40680053

2025

Odontogenesis-associated phosphoprotein (ODAPH) Promotes Ameloblast adhesion and alkaline phosphatase (ALP) expression via LAMC2/ ITGB6/TGF-β1 signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Mingyue Li,Jie Zhang,Shuang Xiao,Xinyang Liu,Shuai Song,Xiaoyuan Ye,Ruonan Bi,Yuguang Gao,Li Zhang

Laboratory investigation; a journal of technical methods and pathology 102:25-37 PubMed34725437

2021

FABP4 activates the JAK2/STAT2 pathway via Rap1a in the homocysteine-induced macrophage inflammatory response in ApoE mice atherosclerosis.

Applications

Unspecified application

Species

Unspecified reactive species

Lingbo Xu,Huiping Zhang,Yanhua Wang,Anning Yang,Xiaoyan Dong,Lingyu Gu,Dayue Liu,Ning Ding,Yideng Jiang

Frontiers in oncology 11:649980 PubMed34178637

2021

MAPK-RAP1A Signaling Enriched in Hepatocellular Carcinoma Is Associated With Favorable Tumor-Infiltrating Immune Cells and Clinical Prognosis.

Applications

Unspecified application

Species

Unspecified reactive species

Hailin Li,Guangyu Han,Xing Li,Bowen Li,Bo Wu,Hongyuan Jin,Lingli Wu,Wei Wang

Oncology reports 42:1815-1824 PubMed31545475

2019

Rap1A promotes esophageal squamous cell carcinoma metastasis through the AKT signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Qinfang Li,Aiping Xu,Yuan Chu,Tao Chen,Hongqi Li,Liqing Yao,Pinghong Zhou,Meidong Xu
View all publications
style
left-column
style
left-column
style
right-column

Alternative Products

Primary Antibodies

AB96223

Anti-RAP1A antibody

Western blot - Anti-RAP1A antibody (AB96223)

  • 0
  • 0

Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB187659

Anti-RAP1A + RAP1B antibody [EPR14814]

RabMAb|Recombinant

Western blot - Anti-RAP1A + RAP1B antibody [EPR14814] (AB187659)

  • 0
  • 0
Primary Antibodies

AB9485

Anti-GAPDH antibody - Loading Control

BOND RX™ Validated|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-GAPDH antibody - Loading Control (AB9485)

  • 5
  • 88
Primary Antibodies

AB76315

Anti-STAT3 (phospho Y705) antibody [EP2147Y]

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunocytochemistry/ Immunofluorescence - Anti-STAT3 (phospho Y705) antibody [EP2147Y] (AB76315)

  • 4
  • 21

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com