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AB96223

Anti-RAP1A antibody

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(5 Publications)

Rabbit Polyclonal RAP1A antibody. Suitable for WB and reacts with Rat, Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human RAP1A aa 1 to C-terminus.

View Alternative Names

KREV1, RAP1A, Ras-related protein Rap-1A, C21KG, G-22K, GTP-binding protein smg p21A, Ras-related protein Krev-1

1 Images
Western blot - Anti-RAP1A antibody (AB96223)
  • WB

Supplier Data

Western blot - Anti-RAP1A antibody (AB96223)

Samples were separated by 12% SDS PAGE.

All lanes:

Western blot - Anti-RAP1A antibody (ab96223) at 1/1000 dilution

All lanes:

C6 Whole cell extract at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 21 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Rat, Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human RAP1A aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P62834

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Zebrafish": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes (PubMed : 17916086). Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. Facilitates the progressive accumulation of CDH1 at mature desmosome junctions via cAMP-dependent signaling and its interaction with PKP3 (PubMed : 25208567). May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions.
See full target information RAP1A
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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Disease markers 2022:9464094 PubMed36157221

2022

EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoli Ding,Lanlan Hou,Huijuan Zhang,Zhiping Chen,Zhanyu Liu,Junjie Gong,Zhixian Tang,Rong Hu

International journal of molecular sciences 23: PubMed35562872

2022

Rap1a Activity Elevated the Impact of Endogenous AGEs in Diabetic Collagen to Stimulate Increased Myofibroblast Transition and Oxidative Stress.

Applications

Unspecified application

Species

Unspecified reactive species

Stephanie D Burr,Christopher C Dorroh,James A Stewart

Cells 10: PubMed33806572

2021

Rap1a Overlaps the AGE/RAGE Signaling Cascade to Alter Expression of α-SMA, p-NF-κB, and p-PKC-ζ in Cardiac Fibroblasts Isolated from Type 2 Diabetic Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Stephanie D Burr,James A Stewart

Human mutation 41:1425-1434 PubMed32442335

2020

The expanding LARS2 phenotypic spectrum: HLASA, Perrault syndrome with leukodystrophy, and mitochondrial myopathy.

Applications

Unspecified application

Species

Unspecified reactive species

Lisa G Riley,Joëlle Rudinger-Thirion,Magali Frugier,Meredith Wilson,Melissa Luig,Thushari Indika Alahakoon,Cheng Yee Nixon,Edwin P Kirk,Tony Roscioli,Sebastian Lunke,Zornitza Stark,Klaas J Wierenga,Sirish Palle,Maie Walsh,Emily Higgs,Susan Arbuckle,Shalini Thirukeswaran,Alison G Compton,David R Thorburn,John Christodoulou

Neoplasma 67:584-594 PubMed32182086

2020

Long noncoding RNA CRNDE promotes proliferation, migration and invasion in prostate cancer through miR-101/Rap1A.

Applications

Unspecified application

Species

Unspecified reactive species

J H Chen,W Tong,X F Pu,J Z Wang
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
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