AB101369

Anti-RAP2B antibody

Name: Anti-RAP2B antibody (ab101369) | Abcam
Brand: Abcam Limited
SKU: AB101369

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(6 Publications)

Rabbit Polyclonal RAP2B antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Recombinant Fragment Protein within Human Ras-related protein Rap-2b aa 1 to C-terminus.

View Alternative Names

Ras-related protein Rap-2b, RAP2B

1 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAP2B antibody (AB101369)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAP2B antibody (AB101369)

Immunohistochemical analysis of paraffin-embedded CL1-0 xenograft, using ab101369 at 1/100 dilution.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human Ras-related protein Rap-2b aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P61225

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "<p>Antigen retrieval using heat mediated 10mM Citrate buffer or Tris-EDTA buffer pH 8.0 is recommended</p>" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Zebrafish": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.

See full target information Ras-related protein Rap-2b

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Cell death & disease 15:675 PubMed39277583

2024

Inhibiting S-palmitoylation arrests metastasis by relocating Rap2b from plasma membrane in colorectal cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Jiangli Zhu,Xize Cao,Zhenshuai Chen,Birou Lai,Lingling Xi,Jinghang Zhang,Shaohui Zhu,Shiqian Qi,Yinming Liang,Fei Cao,Binhui Zhou,Yu Song,Sheng Jiang,Tianyu Wang,Xiaohong Kang,Eryan Kong

Urologia internationalis 107:632-645 PubMed36958293

2023

Hsa_circ_0008035 Knockdown Inhibits Bladder Cancer Progression through miR-1184/RAP2B Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Yang Fu,Kun Liu,Xi Jiang,Lun Zhao,Tianwei Wang

Cell death discovery 9:101 PubMed36944636

2023

The long non-coding RNA PVT1 promotes tumorigenesis of cutaneous squamous cell carcinoma via interaction with 4EBP1.

Applications

Unspecified application

Species

Unspecified reactive species

Rong Li,Dan Huang,Mei Ju,Hong-Ying Chen,Chao Luan,Jia-An Zhang,Kun Chen

Oncology letters 21:314 PubMed33692846

2021

Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Guohong Shi,Zhen Zhang

Molecular medicine reports 23: PubMed33313944

2020

lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis.

Applications

Unspecified application

Species

Unspecified reactive species

Yi Han,Xiaoyan Wang,Enqiang Mao,Boyong Shen,Liang Huang

Tumour biology : the journal of the International 35:9387-94 PubMed24951956

2014

Rap2B promotes migration and invasion of human suprarenal epithelioma.

Applications

Unspecified application

Species

Unspecified reactive species

Jie-Hui Di,De-Bao Qu,Zheng Lu,Lian-Tao Li,Qian Cheng,Yong Xin,Long-Zhen Zhang,Yanping Zhang,Jun-Nian Zheng

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-RAP2B antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAP2B antibody (AB101369)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Complementary Products

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (6)

Product promise