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AB317415

Anti-RBM43 antibody [S03-6I5]

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Rabbit Monoclonal RBM43 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human RBM43.

View Alternative Names

C2orf38, RNA-binding protein 43, RNA-binding motif protein 43

1 Images
Western blot - Anti-RBM43 Antibody [S03-6I5] (AB317415)
  • WB

Supplier Data

Western blot - Anti-RBM43 Antibody [S03-6I5] (AB317415)

All lanes:

Western blot - Anti-RBM43 Antibody [S03-6I5] (ab317415) at 1/1000 dilution

All lanes:

HeLa cell lysate

Predicted band size: 41 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

S03-6I5

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human RBM43.

Q6ZSC3

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Storage buffer
pH: 7.4 Preservative: 0.01% Sodium azide Constituents: 55.08% Water, 40% Glycerol (glycerin, glycerine), 0.98% Tris glycine, 0.88% Sodium chloride, 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

RBM43 or RNA Binding Motif Protein 43 is a protein that plays a role in RNA processing. This protein weighs around 47 kDa. Researchers find RBM43 expression in various tissues with significant levels in the brain heart and liver. It contains RNA-recognition motifs that allow it to interact with RNA molecules. RBM43 modulates splicing events by binding to specific RNA sequences making it a functional part of post-transcriptional modifications.
Biological function summary

The involvement of RNA Binding Motif Protein 43 in RNA processing facilitates efficient gene expression regulation. Although not much is documented about its complex formations its interaction with ribonucleoproteins suggests it may function in complex RNA processing assemblies. By influencing RNA splicing and stability RBM43 affects gene expression levels ultimately contributing to cellular homeostasis.

Pathways

RBM43 plays an instrumental role in the mRNA splicing and processing pathways. It ensures the accuracy and efficiency of RNA maturation and maintains optimal function of the splicing machinery. Proteins like SF3B1 and U2AF2 form part of the family of splicing factors that interact either directly or indirectly with RBM43 in these pathways collectively ensuring the precision of spliceosome assembly and subsequent RNA splicing.

RBM43 appears linked to certain cancers and neurological conditions. Researchers identify an association between the dysregulation of this protein and breast cancer where aberrant splicing events contribute to tumorigenesis. In neurological research scientists suggest a possible connection of RBM43 alterations in neurodegenerative disorders such as Alzheimer's disease influenced through its interaction with splicing-related proteins like hnRNP and FUS. Understanding RBM43's role provides insights into the molecular mechanisms underlying these conditions.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information RBM43
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Product promise

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