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AB150353

Anti-RBMS1 antibody [EPR9825(B)]

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(7 Publications)

Rabbit Recombinant Monoclonal RBMS1 antibody. Suitable for WB and reacts with Human, Mouse, Rat samples. Cited in 7 publications.

View Alternative Names

C2orf12, MSSP, MSSP1, SCR2, RBMS1, Single-stranded DNA-binding protein MSSP-1, Suppressor of CDC2 with RNA-binding motif 2

1 Images
Western blot - Anti-RBMS1 antibody [EPR9825(B)] (AB150353)
  • WB

Unknown

Western blot - Anti-RBMS1 antibody [EPR9825(B)] (AB150353)

All lanes:

Western blot - Anti-RBMS1 antibody [EPR9825(B)] (ab150353) at 1/1000 dilution

Lane 1:

HeLa cell lysate at 10 µg

Lane 2:

HepG2 cell lysate at 10 µg

Lane 3:

Jurkat cell lysate at 10 µg

Lane 4:

C6 cell lysate at 10 µg

Lane 5:

Raw 264.7 cell lysate at 10 µg

Lane 6:

NIH3T3 cell lysate at 10 µg

Predicted band size: 45 kDa

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  • Carrier free

    Anti-RBMS1 antibody [EPR9825(B)] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR9825(B)

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Rat, Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purity
Tissue culture supernatant
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

RBMS1 or RNA-binding motif single-stranded interacting protein 1 is a protein that plays an important role in binding single-stranded RNA and DNA. It has a molecular mass of approximately 45 kDa and is widely expressed in various tissues including but not limited to the brain liver and heart. Functionally RBMS1 contributes to a range of cellular processes by regulating the stability and translation of its bound nucleic acids.
Biological function summary

The RNA-binding capabilities of RBMS1 enable it to exert influence over gene expression and cellular proliferation. RBMS1 interacts with multiple other proteins becoming part of larger complexes that facilitate its regulatory actions. Complex formation with diverse molecular partners allows RBMS1 to influence different aspects of RNA metabolism and stability impacting cellular growth and development.

Pathways

The involvement of RBMS1 is notable in pathways regulating cell cycle and apoptosis. RBMS1 associates with components of the cell cycle control machinery affecting checkpoint regulation and cell proliferation. Its interaction with proteins like MYC and other cell cycle pathogenic elements highlights its role in the fine-tuning of growth-related cascades and programmed cell death mechanisms.

RBMS1 is associated with certain types of cancer notably those where gene expression misregulation is a factor. Altered expression or mutation of RBMS1 may contribute to oncogenic processes alongside proteins such as KRAS facilitating tumor progression and metastasis. Furthermore RBMS1 dysregulation can influence neurological disorders possibly through pathways that involve cell death such as those linked to neurodegenerative disease markers.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.
See full target information RBMS1
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Publications (7)

Recent publications for all applications. Explore the full list and refine your search

Oncology letters 30:450 PubMed40747376

2025

Identification of key ferroptosis-related genes associated with the development of gastric cancer: Prognostic models, molecular mechanisms and potential treatment strategies.

Applications

Unspecified application

Species

Unspecified reactive species

Hui Wang,Hang Chen,Jianjun Liu,Dan Zhang,Da Wang,Minshan Huang,Mengwei Li,Suyu He,Lanqing Ma

Discover oncology 15:548 PubMed39392522

2024

RBMS1 interference inhibits malignant progression of glioblastoma cells and promotes ferroptosis.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaosong Liang,Gang Wang,Chunxiao Xue,Yifu Zhou

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11:e2307122 PubMed38342601

2024

RBMS1 Coordinates with the mA Reader YTHDF1 to Promote NSCLC Metastasis through Stimulating S100P Translation.

Applications

Unspecified application

Species

Unspecified reactive species

Yu Sun,Dan Chen,Siwen Sun,Menglin Ren,Liang Zhou,Chaoqun Chen,Jinyao Zhao,Huanhuan Wei,Qingzhi Zhao,Yangfan Qi,Jinrui Zhang,Ge Zhang,Han Liu,Qingkai Yang,Quentin Liu,Yang Wang,Wenjing Zhang

Molecules and cells 45:588-602 PubMed35754370

2022

RNA Binding Protein Rbms1 Enables Neuronal Differentiation and Radial Migration during Neocortical Development by Binding and Stabilizing the RNA Message for Efr3a.

Applications

Unspecified application

Species

Unspecified reactive species

Khadija Habib,Kausik Bishayee,Jieun Kang,Ali Sadra,Sung-Oh Huh

Cell death and differentiation 29:2247-2261 PubMed35538152

2022

Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Jinrui Zhang,Ge Zhang,Wenjing Zhang,Lu Bai,Luning Wang,Tiantian Li,Li Yan,Yang Xu,Dan Chen,Wenting Gao,Chuanzhou Gao,Chaoqun Chen,Menglin Ren,Yuexia Jiao,Hongqiang Qin,Yu Sun,Lili Zhi,Yangfan Qi,Jinyao Zhao,Quentin Liu,Han Liu,Yang Wang

Nature communications 12:5208 PubMed34471108

2021

Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.

Applications

Unspecified application

Species

Unspecified reactive species

Kai P Hoefig,Alexander Reim,Christian Gallus,Elaine H Wong,Gesine Behrens,Christine Conrad,Meng Xu,Lisa Kifinger,Taku Ito-Kureha,Kyra A Y Defourny,Arie Geerlof,Josef Mautner,Stefanie M Hauck,Dirk Baumjohann,Regina Feederle,Matthias Mann,Michael Wierer,Elke Glasmacher,Vigo Heissmeyer

Nucleic acids research 42:e13 PubMed24157833

2013

An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins.

Applications

IP, WB

Species

Human, Human

Kathrin Leppek,Georg Stoecklin
View all publications
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Product promise

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