Rabbit Polyclonal RDM1 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human RDM1 aa 1-100.
View Alternative Names
RAD52B, RDM1, RAD52 motif-containing protein 1, RAD52 homolog B
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RDM1 antibody (AB254803)
Paraffin-embedded human testis tissue stained for RDM1 using ab254803 at 1/500 dilution in immunohistochemical analysis.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RDM1 antibody (AB254803)
Paraffin-embedded human uterine cervix tissue stained for RDM1 using ab254803 at 1/500 dilution in immunohistochemical analysis. Low expression as expected.
Reactivity data
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Supplementary information
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Biological function summary
RDM1 aids in the restoration of damaged DNA and participates in homologous recombination repair. It forms part of a complex that detects and responds to DNA damage contributing to cell cycle regulation. By working together with proteins like RAD52 RDM1 reinforces the cellular ability to manage genetic lesions enabling cells to maintain growth and replication integrity under stress conditions.
Pathways
The actions of RDM1 are integral to the DNA damage response pathway. This pathway links to mechanisms that control cell cycle checkpoints. The protein intersects with the homologous recombination repair pathway cooperating with other essential proteins such as BRCA2. These alliances highlight RDM1's role in shaping effective responses to genomic injury facilitating accurate DNA repair and preventing mutations.
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Target data
Publications (1)
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World journal of surgical oncology 19:246 PubMed34404391
2021
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Unspecified application
Species
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