Rat Monoclonal CD44 antibody - conjugated to redFluor™ 710. Suitable for Flow Cyt and reacts with Mouse samples.
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin
Flow Cyt | |
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Mouse | Tested |
Species | Dilution info | Notes |
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Species Mouse | Dilution info - | Notes 0.5 μg: The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system. |
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Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases (PubMed:25065622, PubMed:8343954). Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion (By similarity).
CD44, Ly-24, Cd44, CD44 antigen, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Lymphocyte antigen 24, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, ECMR-III, PGP-1, PGP-I
Rat Monoclonal CD44 antibody - conjugated to redFluor™ 710. Suitable for Flow Cyt and reacts with Mouse samples.
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin
Purified from TCS via affinity chromatography.
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Flow Cytometric analysis of C57Bl/6 bone marrow cells staining CD44 using 0.5 μg ab242265 (solid line) or 0.5 μg redFluor™ 710 Rat IgG2b isotype control (dashed line).
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