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AB251069

Anti-REEP2 antibody [EPR16080] - BSA and Azide free

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(1 Publication)

Rabbit Recombinant Monoclonal REEP2 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 1 publication.

View Alternative Names

C5orf19, SGC32445, REEP2, Receptor expression-enhancing protein 2

2 Images
Western blot - Anti-REEP2 antibody [EPR16080] - BSA and Azide free (AB251069)
  • WB

Supplier Data

Western blot - Anti-REEP2 antibody [EPR16080] - BSA and Azide free (AB251069)

This data was developed using ab191410, the same antibody clone in a different buffer formulation.

All lanes:

Western blot - Anti-REEP2 antibody [EPR16080] (<a href='/en-us/products/primary-antibodies/reep2-antibody-epr16080-ab191410'>ab191410</a>) at 1/10000 dilution

All lanes:

Y-79 cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/1000 dilution

Predicted band size: 28 kDa

false

Western blot - Anti-REEP2 antibody [EPR16080] - BSA and Azide free (AB251069)
  • WB

Supplier Data

Western blot - Anti-REEP2 antibody [EPR16080] - BSA and Azide free (AB251069)

This data was developed using ab191410, the same antibody clone in a different buffer formulation.

All lanes:

Western blot - Anti-REEP2 antibody [EPR16080] (<a href='/en-us/products/primary-antibodies/reep2-antibody-epr16080-ab191410'>ab191410</a>) at 1/1000 dilution

Lane 1:

SH-SY5Y cell lysate at 20 µg

Lane 2:

Human fetal brain tissue lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/1000 dilution

Predicted band size: 28 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR16080

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
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Product details

ab251069 is the carrier-free version of ab191410.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Compatibility
This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.

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Properties and storage information

Form
Liquid
Storage buffer
pH: 7.2 - 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

REEP2 also known as Receptor Expression Enhancing Protein 2 plays an important role in shaping membrane structures such as the endoplasmic reticulum. It has a molecular mass of approximately 24 kDa. This protein is expressed in various tissues including the central nervous system and peripheral tissues. REEP2 assists in modulating the surface expression of receptors facilitating their proper localization within the cell.
Biological function summary

Proteins like REEP2 participate in the formation of tubular endoplasmic reticulum structures. It is often part of a complex with other proteins like the Atlastin family which contributes to the shaping and remodeling of cellular membranes. REEP2 helps in maintaining cellular processes that depend on intact membrane architecture supporting the dynamic nature of the cellular environment.

Pathways

Cellular processes involving endoplasmic reticulum development highlight the function of proteins such as REEP2. It is intricately involved in the endoplasmic reticulum network pathways. These pathways often include interactions with proteins such as Reticulon which also contribute to membrane structure. By participating in these pathways REEP2 supports intracellular processes necessary for maintaining cellular homeostasis.

Proteins like REEP2 have connections to neurological conditions such as hereditary spastic paraplegia (HSP). Mutations in REEP2 can lead to the degeneration of nerves causing motility issues. Additionally its interaction with Spastin has been associated with severe phenotypes of HSP highlighting its critical role in maintaining neural integrity. Understanding REEP2's function and relationship to disorders offers potential avenues for therapeutic exploration.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors (By similarity).
See full target information REEP2
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of cellular and molecular medicine 25:8127-8139 PubMed34350711

2021

Overexpression of let-7d explains down-regulated KDM3A and ENO2 in the pathogenesis of preeclampsia.

Applications

Unspecified application

Species

Unspecified reactive species

Qian Xu,Yonghui Song,Lili Lu
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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