AB233210

Anti-REG1B antibody

Name: Anti-REG1B antibody (ab233210) | Abcam
Brand: Abcam Limited
SKU: AB233210
Price: 525 USD
Availability: InStock

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(1 Publication)

Rabbit Polyclonal REG1B antibody. Suitable for WB, IHC-P and reacts with Mouse, Recombinant fragment - Human, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human REG1B.

View Alternative Names

PSPS2, REGL, REG1B, Lithostathine-1-beta, Pancreatic stone protein 2, Regenerating islet-derived protein 1-beta, Regenerating protein I beta, PSP-2, REG-1-beta

5 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REG1B antibody (AB233210)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REG1B antibody (AB233210)

Formalin-fixed, paraffin-embedded human pancreas tissue stained for REG1B using ab233210 at 30 μg/ml in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REG1B antibody (AB233210)

Formalin-fixed, paraffin-embedded human stomach tissue stained for REG1B using ab233210 at 30 μg/ml in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REG1B antibody (AB233210)

Formalin-fixed, paraffin-embedded human stomach cancer tissue stained for REG1B using ab233210 at 30 μg/ml in immunohistochemical analysis. DAB staining.

Supplier Data

Western blot - Anti-REG1B antibody (AB233210)

All lanes:

Western blot - Anti-REG1B antibody (ab233210) at 5 µg/mL

All lanes:

Recombinant human REG1B protein

Predicted band size: 19 kDa

false

Supplier Data

Western blot - Anti-REG1B antibody (AB233210)

All lanes:

Western blot - Anti-REG1B antibody (ab233210) at 3 µg/mL

Lane 1:

Human urine

Lane 2:

Mouse pancreas tissue lysate

Secondary

All lanes:

HRP-Linked Guinea pig anti-rabbit at 1/2000 dilution

Predicted band size: 19 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human, Mouse

Applications

IHC-P, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human REG1B.

P48304

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Recombinant fragment - Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

Antigen-specific affinity chromatography followed by Protein A affinity chromatography.

Storage buffer

pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

REG1B also known as Regenerating islet-derived protein 1B is a small secretory protein with a molecular mass of approximately 18 kDa. This protein is expressed mainly in the pancreas with some expression noted in other tissues such as the gastrointestinal tract. It plays a role in the secretion and regulation of various cellular processes. REG1B belongs to the Reg family of proteins which function as lectins that bind to specific carbohydrate molecules.

Biological function summary

REG1B involves itself in pancreatic repair and regeneration. Its involvement in cell proliferation suggests that it plays a part in tissue recovery. REG1B is not typically part of a larger complex but it may interact with other proteins to carry out its function. Its presence has been noted during the regenerative processes in acinar cells of the pancreas following injury or stress proposing its participation in tissue defense mechanisms.

Pathways

The role of REG1B becomes evident in processes relating to pancreatic health and diabetes. It plays a role in the inflammatory and cellular stress response pathways. REG1B can also interact with other family members like REG1A to coordinate response activities contributing to cell signaling and regeneration potentially through modulation of local inflammation and cellular growth signals.

REG1B associates closely with conditions involving pancreatic disorders such as pancreatitis and pancreatic cancer. The protein might stimulate or inhibit cellular pathways that can contribute to the development or progression of these conditions. REG1B links to inflammatory process related proteins such as cytokines and its expression levels may change during disease progression indicating a potential biomarker role.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.

See full target information REG1B

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nutrition & metabolism 22:109 PubMed41029463

2025

mTOR-autophagy axis regulation by intermittent fasting promotes skeletal muscle growth and differentiation.

Applications

Unspecified application

Species

Unspecified reactive species

Chen Xinyan,Wu Yajie,He Shangfan,Yang Yuefei,Li Junwei,Zhu Jiaqiao,Ju Huiming

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-REG1B antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REG1B antibody (AB233210)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REG1B antibody (AB233210)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REG1B antibody (AB233210)

Western blot - Anti-REG1B antibody (AB233210)

Western blot - Anti-REG1B antibody (AB233210)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Complementary Products

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

Product promise