JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB119501

Anti-Resistin antibody

Be the first to review this product! Submit a review

|

(6 Publications)

Rabbit Polyclonal Resistin antibody. Suitable for WB and reacts with Mouse samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Mouse Retn.

View Alternative Names

Fizz3, Retn, Resistin, Adipose tissue-specific secretory factor, Adipose-specific cysteine-rich secreted protein A12-alpha, Cysteine-rich secreted protein FIZZ3, ADSF

1 Images
Western blot - Anti-Resistin antibody (AB119501)
  • WB

Unknown

Western blot - Anti-Resistin antibody (AB119501)

All lanes:

Western blot - Anti-Resistin antibody (ab119501) at 1 µg/mL

Lane 1:

Recombinant Mouse Resistin protein at 0.01 µg

Lane 2:

Recombinant Mouse Resistin protein at 0.005 µg

Predicted band size: 11 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse

Applications

WB

applications

Immunogen

Synthetic Peptide within Mouse Retn. The exact immunogen used to generate this antibody is proprietary information.

Q99P87

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p>The detection limit for Resistin is approximately 2.5ng/lane under non-reducing and reducing conditions.</p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
Preservative: 0.025% Sodium azide, 0.025% Thimerosal (merthiolate) Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Disodium hydrogenorthophosphate
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Resistin also known as FIZZ3 or ADSF is a protein with a mass of approximately 12.5 kDa. It is mainly expressed in adipose tissue and secreted by adipocytes. In human beings it is also found in inflammatory zones like macrophages and the placenta. Resistin functions as a signaling molecule or cytokine which plays roles in inflammation and metabolism.
Biological function summary

Resistin affects glucose homeostasis and has been shown to modulate insulin resistance. It does not function as part of a larger protein complex but instead acts through specific receptors on cell surfaces. Resistin influences several cellular processes including energy balance and the modulation of inflammatory responses.

Pathways

Several processes contribute to the detailed function of resistin. It is involved in the insulin signaling pathway and the inflammatory pathway. Resistin interacts with proteins and receptors like TLR4 which have key roles in inflammatory response signaling and metabolic regulation. These interactions can disrupt insulin signaling and glucose uptake in many cell types.

Resistin has connections to type 2 diabetes and obesity. Its role in insulin resistance makes it a significant molecule in the pathophysiology of type 2 diabetes. Additionally resistin can influence obesity through its effect on energy balance and fat distribution. Resistin's relationship with proteins like TNF-alpha and IL-6 further emphasizes its role in linking metabolic syndrome with chronic inflammatory states.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes.
See full target information Retn
style
left-column

Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Diabetology & metabolic syndrome 13:150 PubMed34952629

2021

Dietary supplementation of inulin alleviates metabolism disorders in gestational diabetes mellitus mice via RENT/AKT/IRS/GLUT4 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Miao Miao,Yongmei Dai,Can Rui,Yuru Fan,Xinyan Wang,Chong Fan,Juan Mu,Wenwen Hou,Zhiyong Dong,Ping Li,Guiju Sun,Xin Zeng

PLoS biology 18:e3000739 PubMed33370269

2020

Increased prostaglandin-D2 in male STAT3-deficient hearts shifts cardiac progenitor cells from endothelial to white adipocyte differentiation.

Applications

Unspecified application

Species

Unspecified reactive species

Elisabeth Stelling,Melanie Ricke-Hoch,Sergej Erschow,Steve Hoffmann,Anke Katharina Bergmann,Maren Heimerl,Stefan Pietzsch,Karin Battmer,Alexandra Haase,Britta Stapel,Michaela Scherr,Jean-Luc Balligand,Ofer Binah,Denise Hilfiker-Kleiner

Phytomedicine : international journal of phytother 61:152860 PubMed31048126

2019

Effect and mechanism of psoralidin on promoting osteogenesis and inhibiting adipogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Hui-Juan Cao,Cai-Rong Li,Lin-Ying Wang,Reihane Ziadlou,Sibylle Grad,Yan Zhang,Yan Cheng,Yu-Xiao Lai,Xin-Sheng Yao,Mauro Alini,Ling Qin,Xin-Luan Wang

Frontiers in physiology 9:1297 PubMed30369883

2018

Increased Expression of Resistin in MicroRNA-155-Deficient White Adipose Tissues May Be a Possible Driver of Metabolically Healthy Obesity Transition to Classical Obesity.

Applications

Unspecified application

Species

Unspecified reactive species

Candice Johnson,Charles Drummer,Anthony Virtue,Tracy Gao,Susu Wu,Miguel Hernandez,Lexy Singh,Hong Wang,Xiao-Feng Yang

Endocrinology 158:3540-3552 PubMed28938461

2017

Adipokines and Their Receptors Are Widely Expressed and Distinctly Regulated by the Metabolic Environment in the Prostate of Male Mice: Direct Role Under Normal and Tumoral Conditions.

Applications

Unspecified application

Species

Unspecified reactive species

André Sarmento-Cabral,Fernando L-López,Raúl M Luque

PloS one 11:e0151916 PubMed26986475

2016

Inflammation Activation Contributes to Adipokine Imbalance in Patients with Acute Coronary Syndrome.

Applications

WB

Species

Unspecified reactive species

Rong Li,Lu-zhu Chen,Shui-ping Zhao,Xian-sheng Huang
View all publications
style
left-column
style
left-column
style
right-column

Alternative Products

Primary Antibodies

AB168137

Anti-Resistin antibody

Immunocytochemistry/ Immunofluorescence - Anti-Resistin antibody (AB168137)

  • 3
  • 1
Primary Antibodies

AB216840

Anti-Resistin antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Resistin antibody (AB216840)

  • 0
  • 0
Primary Antibodies

AB219096

Anti-Resistin antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Resistin antibody (AB219096)

  • 0
  • 0

Complementary Products

Assay Kits

AB183364

Human Resistin ELISA Kit

SimpleStep

ELISA - Human Resistin ELISA Kit (AB183364)

  • 0
  • 0
Primary Antibodies

AB133347

Anti-Adiponectin antibody [EPR3218]

RabMAb|Recombinant

Western blot - Anti-Adiponectin antibody [EPR3218] (AB133347)

  • 0
  • 0
Assay Kits

AB205574

Mouse Resistin ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Mouse Resistin ELISA Kit (AB205574)

  • 0
  • 0
Primary Antibodies

AB209483

Anti-UCP1 antibody [EPR20381]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-UCP1 antibody [EPR20381] (AB209483)

  • 5
  • 4
Primary Antibodies

AB181298

Anti-Leptin antibody [EPR16848-34]

RabMAb|Recombinant

Blocking - Anti-Leptin antibody [EPR16848-34] (AB181298)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com