JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB20531

Anti-Respiratory Syncytial Virus antibody

Be the first to review this product! Submit a review

|

(3 Publications)

Goat Polyclonal Respiratory Syncytial Virus antibody. Suitable for ICC, ELISA, FuncS (Neut/Block) and reacts with Respiratory syncytial virus samples. Cited in 3 publications.

View Alternative Names

RS virus, RSV

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Respiratory syncytial virus

Applications

FuncS (Neut/Block), ICC, ELISA

applications

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "FuncSNeutBlock" : {"fullname" : "Functional Studies (Neut/Block)", "shortname":"FuncS (Neut/Block)"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Respiratory syncytial virus": { "ICC-species-checked": "guaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "FuncSNeutBlock-species-checked": "guaranteed", "FuncSNeutBlock-species-dilution-info": "", "FuncSNeutBlock-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purity
IgG fraction
Storage buffer
pH: 7.2 Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Respiratory Syncytial Virus (RSV) is a negative-sense single-stranded RNA virus known to cause respiratory infections. It belongs to the Paramyxoviridae family and is sometimes referred to by its alternate names like Human Orthopneumovirus. RSV is approximately 15 kb in size. It is predominantly expressed in the respiratory tract where it attacks epithelial cells leading to infection. The virus's ability to form a syncytium a large multinucleate cell is one of its mechanical strategies to aid in the spread across the host cells.
Biological function summary

The virus propagates efficiently within the host tissue leading to serious respiratory illness in infants and young children. RSV is not part of a specific complex but it engages host cellular machinery to promote its replication and prevent immune detection. The fusion (F) protein of RSV plays a critical role in mediating membrane fusion facilitating viral entry into the host cells. The involvement of viral proteins in modulating host immune responses is significant for the virus's life cycle.

Pathways

Respiratory infections caused by RSV connect to the host's immune signaling pathways including the toll-like receptor (TLR) pathways and the interferon response pathway. The interaction of RSV proteins with these pathways leads to an increased inflammatory response. Proteins such as the RSV G protein interface with the chemokine receptor pathway which helps in modulation of the immune system to allow viral persistence. These interactions demonstrate the virus's strategies to evade immune surveillance and promote infection.

Respiratory syncytial virus is a major cause of bronchiolitis and pneumonia in infants and young children. The virus's activity in the respiratory tract contributes to severe inflammation and cell damage which can lead to hospitalization. Other proteins like RSV M protein are involved in virus assembly and budding and they passively influence disease progression by impacting viral load and the host's immune response. Understanding these interactions is important for developing therapeutic strategies including anti-RSV monoclonal antibodies like palivizumab (2F7) which target prominent viral components to prevent severe disease outcomes.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

See full target information Respiratory Syncytial Virus
style
left-column

Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Journal of virology 93: PubMed30651356

2019

Effects of Alterations to the CX3C Motif and Secreted Form of Human Respiratory Syncytial Virus (RSV) G Protein on Immune Responses to a Parainfluenza Virus Vector Expressing the RSV G Protein.

Applications

Unspecified application

Species

Unspecified reactive species

Bo Liang,Barbora Kabatova,Juraj Kabat,David W Dorward,Xiang Liu,Sonja Surman,Xueqiao Liu,Annie Park Moseman,Ursula J Buchholz,Peter L Collins,Shirin Munir

Journal of virology 90:1705-17 PubMed26608311

2015

The Interferon Type I/III Response to Respiratory Syncytial Virus Infection in Airway Epithelial Cells Can Be Attenuated or Amplified by Antiviral Treatment.

Applications

Unspecified application

Species

Unspecified reactive species

K M McCutcheon,R Jordan,M E Mawhorter,S L Noton,J G Powers,R Fearns,T Cihlar,M Perron

Archives of virology 159:1067-77 PubMed24292020

2013

A recombinant influenza virus vaccine expressing the F protein of respiratory syncytial virus.

Applications

Unspecified application

Species

Unspecified reactive species

Wendy Fonseca,Makoto Ozawa,Masato Hatta,Esther Orozco,Máximo B Martínez,Yoshihiro Kawaoka
View all publications
style
left-column
style
left-column
style
right-column

Alternative Products

Primary Antibodies

AB12253

Anti-Respiratory Syncytial Virus antibody

  • 0
  • 0
Primary Antibodies

AB10018

Anti-Respiratory Syncytial Virus antibody [9C5]

  • 0
  • 0
Primary Antibodies

AB20686

HRP Anti-Respiratory Syncytial Virus antibody

  • 0
  • 0
Primary Antibodies

AB19986

Biotin Anti-Respiratory Syncytial Virus antibody

  • 0
  • 0
Primary Antibodies

AB20391

FITC Anti-Respiratory Syncytial Virus antibody

  • 0
  • 0
Primary Antibodies

AB20745

Anti-Respiratory Syncytial Virus antibody

  • 0
  • 0
Primary Antibodies

AB43812

Anti-Respiratory Syncytial Virus antibody [2F7]

Immunocytochemistry/ Immunofluorescence - Anti-Respiratory Syncytial Virus antibody [2F7] (AB43812)

  • 5
  • 1

Complementary Products

Primary Antibodies

AB94965

Anti-Respiratory Syncytial Virus Phosphoprotein antibody [RSVH102]

  • 0
  • 0
Primary Antibodies

AB183497

Anti-VSV-G tag antibody [EPR12997]

RabMAb|Recombinant|Lab Essentials

Western blot - Anti-VSV-G tag antibody [EPR12997] (AB183497)

  • 4
  • 2
Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

  • 5
  • 15
Primary Antibodies

AB313343

Anti-Influenza A Virus Nucleoprotein antibody [EPR28253-17]

20ul selling size|RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-Influenza A Virus Nucleoprotein antibody [EPR28253-17] (AB313343)

  • 5
  • 1

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com