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AB189222

Anti-RNase 7 antibody [3C2]

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(1 Publication)

Mouse Monoclonal RNase 7 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Native Full Length Protein corresponding to Human RNASE7.

View Alternative Names

UNQ2516/PRO6006, RNASE7, Ribonuclease 7, RNase 7, Skin-derived antimicrobial protein 2, SAP-2

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [3C2] (AB189222)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [3C2] (AB189222)

Immunohistochemical analysis of paraffin-embedded human skin tissue labeling RNase 7 antibody with ab189222. Biotinylated anti-mouse antibody was used as secondary antibody. Streptavidin-HRP conjugate was used for visualization

Western blot - Anti-RNase 7 antibody [3C2] (AB189222)
  • WB

Supplier Data

Western blot - Anti-RNase 7 antibody [3C2] (AB189222)

Lane 1 : Non-reduced conditions; Lane 2 : Reduced conditions

Lane 1:

Western blot - Anti-RNase 7 antibody [3C2] (ab189222) at 1/500 dilution

Lane 2:

Western blot - Anti-RNase 7 antibody [3C2] (ab189222) at 1/200 dilution

All lanes:

Human RNase 7 expressed by CHOEBNALT85 cell line (cell culture supernatant) at 10 µL

Predicted band size: 17 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

3C2

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Native Full Length Protein corresponding to Human RNASE7.

Q9H1E1

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/200 - 1/2000", "WB-species-notes": "<p>1/500 to 1/2000 under non-reducing conditions; 1/200 to 1/1000 under reducing conditions.</p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "<p></p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Exhibits a potent RNase activity (PubMed : 12244054, PubMed : 12527768, PubMed : 17150966). Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium (PubMed : 12244054, PubMed : 12527768, PubMed : 17150966, PubMed : 25075772, PubMed : 33818125). Causes loss of bacterial membrane integrity (PubMed : 17150966). Probably contributes to urinary tract sterility (PubMed : 25075772). Bactericidal activity is independent of RNase activity (PubMed : 17150966).
See full target information RNASE7

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Alzheimer's research & therapy 17:81 PubMed40229846

2025

Novel CSF β-synuclein-specific assays signal early synaptic degeneration in Alzheimer's disease.

Applications

Unspecified application

Species

Unspecified reactive species

Sherif Bayoumy,Julie Goossens,Charlotte De Rocker,Senna Y Sie,Nolan J Barrett,Wiesje M van der Flier,Charlotte E Teunissen,Eugeen Vanmechelen,Inge M W Verberk
View all publications

Product promise

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