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AB205565

Anti-RNase 7 antibody [4C4]

4

(3 Reviews)

|

(1 Publication)

Mouse Monoclonal RNase 7 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human RNASE7.

View Alternative Names

UNQ2516/PRO6006, RNASE7, Ribonuclease 7, RNase 7, Skin-derived antimicrobial protein 2, SAP-2

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-RNase 7 antibody [4C4] (AB205565)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-RNase 7 antibody [4C4] (AB205565)

Immunofluorescence analysis of U2OS cells labeling RNAase 7 with ab205565 at 0.5 μg/mL. Nuclei were counterstained by DAPI. Left image; U2OS cells expressing RNAase 7. Right image; Negative control (non-transfected U2OS cells).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [4C4] (AB205565)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [4C4] (AB205565)

Immunohistochemical analysis of paraffin-embedded human skin tissue tissue labeling RNAase 7 with ab205565 at 1/500 dilution. Biotinylated anti-mouse antibody was used as secondary antibody. Streptavidin-HRP conjugate was used for visualization.

Western blot - Anti-RNase 7 antibody [4C4] (AB205565)
  • WB

Supplier Data

Western blot - Anti-RNase 7 antibody [4C4] (AB205565)

All lanes:

Western blot - Anti-RNase 7 antibody [4C4] (ab205565) at 2 µg/mL

Lane 1:

CHOEBNALT85 cell line lysate; non-reduced conditions at 10 µL

Lane 2:

CHOEBNALT85 cell line lysate; reduced conditions at 10 µL

Lane 3:

Protein ladder

Predicted band size: 17 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

4C4

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

ICC/IF, IHC-P, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human RNASE7.

Q9H1E1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-2 µg/mL", "WB-species-notes": "<p>WB in non-reduced conditions.</p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.5-20 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Exhibits a potent RNase activity (PubMed : 12244054, PubMed : 12527768, PubMed : 17150966). Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium (PubMed : 12244054, PubMed : 12527768, PubMed : 17150966, PubMed : 25075772, PubMed : 33818125). Causes loss of bacterial membrane integrity (PubMed : 17150966). Probably contributes to urinary tract sterility (PubMed : 25075772). Bactericidal activity is independent of RNase activity (PubMed : 17150966).
See full target information RNASE7
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

International journal of pediatric otorhinolaryngo 110:100-104 PubMed29859567

2018

Tonsillar antimicrobial peptide (AMP) expression profiles of periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis (PFAPA) patients.

Applications

IHC-P

Species

Human

Umut Gazi,Martha Emmanuel Agada,Hanife Ozkayalar,Ceyhun Dalkan,Burcin Sanlidag,Mustafa Asım Safak,Gamze Mocan,Nerin Onder Bahceciler
View all publications
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Product promise

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