Mouse Monoclonal RNase 7 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human RNASE7 aa 1 to C-terminus.
Images
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (AB154143), expandable thumbnail](https://content.abcam.com/products/images/rnase-7-antibody-cl0224-ab154143--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img118129.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (AB154143)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (AB154143), expandable thumbnail](https://content.abcam.com/products/images/rnase-7-antibody-cl0224-ab154143--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img104337.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (AB154143)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (AB154143), expandable thumbnail](https://content.abcam.com/products/images/rnase-7-antibody-cl0224-ab154143--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img127401.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (AB154143)")
Publications
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- Acta histochemica et cytochemica 52:35-432019Immunohistochemical Localization of RNase 7 in Normal and Inflamed Oral Epithelia and Salivary Glands.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPuja Neopane et. al.PubMed 31341339
- Photodermatology, photoimmunology & photomedicine 34:137-1442017Unique profile of antimicrobial peptide expression in polymorphic light eruption lesions compared to healthy skin, atopic dermatitis, and psoriasis.Applications:IHC-PReactive species:HumanVijayKumar Patra,Gerlinde Mayer,Alexandra Gruber-Wackernagel,Michael Horn,Serena Lembo,Peter WolfPubMed 29044786
Key facts
- Isotype
- IgG2a
- Host species
- Mouse
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- Recombinant Fragment Protein within Human RNASE7 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q9H1E1
Reactivity data
Select an application| IHC-P | |
|---|---|
| Human | Tested |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/50.00000 - 1/200.00000 | Notes Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Associated Products
Select an associated product type
3 products for Alternative Product
Target data
Function
Exhibits a potent RNase activity (PubMed:12244054, PubMed:12527768, PubMed:17150966). Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium (PubMed:12244054, PubMed:12527768, PubMed:17150966, PubMed:25075772, PubMed:33818125). Causes loss of bacterial membrane integrity (PubMed:17150966). Probably contributes to urinary tract sterility (PubMed:25075772). Bactericidal activity is independent of RNase activity (PubMed:17150966).
Alternative names
UNQ2516/PRO6006, RNASE7, Ribonuclease 7, RNase 7, Skin-derived antimicrobial protein 2, SAP-2
Recommended products
Mouse Monoclonal RNase 7 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human RNASE7 aa 1 to C-terminus.
Key facts
- Isotype
- IgG2a
- Host species
- Mouse
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- Recombinant Fragment Protein within Human RNASE7 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q9H1E1
- Clone number
- CL0224
- Purification technique
- Affinity purification Protein A
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
3 product images
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143), expandable thumbnail](https://content.abcam.com/products/images/rnase-7-antibody-cl0224-ab154143--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img118129.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143)
Immunohistochemical analysis of Human skin tissue labeling RNase 7 with ab154143 at 1/50 dilution.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143), expandable thumbnail](https://content.abcam.com/products/images/rnase-7-antibody-cl0224-ab154143--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img104337.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143)
Immunohistochemical analysis of Human kidney tissue labeling RNase 7 with ab154143 at 1/50 dilution.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143), expandable thumbnail](https://content.abcam.com/products/images/rnase-7-antibody-cl0224-ab154143--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img127401.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143)
Immunohistochemical analysis of Human fallopian tube tissue labeling RNase 7 with ab154143 at 1/50 dilution.
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