Rabbit Polyclonal RNASE4 antibody. Suitable for IHC-P and reacts with Rat samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human RNASE4 aa 50-100 conjugated to Keyhole Limpet Haemocyanin.
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RNS4, RNASE4, Ribonuclease 4, RNase 4
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNASE4 antibody (AB214293)
Immunohistochemical analysis of formalin-fixed paraffin-embedded rat lung tissue, labeling RNASE4 using ab214293 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.
Reactivity data
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Supplementary information
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Biological function summary
RNase 4 participates in the maintenance of extracellular RNA equilibrium which is important for overall cellular health. It does not typically form complexes like some other ribonucleases do. It helps control RNA turnover by degrading extracellular RNA preventing the accumulation of potentially harmful nucleic acids in the extracellular environment. This activity supports other cellular functions by modulating levels of specific RNA molecules.
Pathways
RNase 4 plays a role in the regulation of nucleic acid metabolism pathways. It works alongside other enzymes such as RNase A to manage RNA turnover which is a critical aspect of gene expression regulation and cellular homeostasis. By influencing these pathways RNase 4 indirectly affects processes involved in the management of cellular stress responses and apoptotic pathways.
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Publications (1)
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American journal of physiology. Renal physiology 320:F972-F983 PubMed33818125
2021
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