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AB111174

Anti-ROR1 antibody

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(5 Publications)

Goat Polyclonal ROR1 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human ROR1 aa 900 to C-terminus.

View Alternative Names

NTRKR1, ROR1, Inactive tyrosine-protein kinase transmembrane receptor ROR1

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ROR1 antibody (AB111174)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ROR1 antibody (AB111174)

ab111174, at 3 µg/ml, staining ROR1 in formalin fixed, paraffin embedded Human prostate tissue by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase streptavidin and chromogen.

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human ROR1 aa 900 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q01973

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "3-6 µg/mL", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 0.5% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed : 25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed : 25029443, PubMed : 27162350). In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells (PubMed : 27162350). Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling (PubMed : 36949068).
See full target information ROR1
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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Biomarker research 13:17 PubMed39849645

2025

ROR1 CAR-T cells and ferroptosis inducers orchestrate tumor ferroptosis via PC-PUFA2.

Applications

Unspecified application

Species

Unspecified reactive species

Dan Li,Wenjie Zhang,Ruiheng Wang,Shufeng Xie,Yixin Wang,Wanxin Guo,Zixuan Huang,Chaoqun Lu,Liang Shan,Han Liu,Lifang Ma,Xumin Hou,Zhenshu Xu,Jiayi Wang

Nucleic acids research 53: PubMed39657788

2024

Novel BRCA1-PLK1-CIP2A axis orchestrates homologous recombination-mediated DNA repair to maintain chromosome integrity during oocyte meiosis.

Applications

Unspecified application

Species

Unspecified reactive species

Crystal Lee,Jeong Su Oh

Allergologia et immunopathologia 51:124-134 PubMed37169570

2023

exacerbates psoriasis-like inflammation by promoting Th17 and Th1 cells activation through regulating transcription.

Applications

Unspecified application

Species

Unspecified reactive species

Huanhuan Zhang,Cuimin Ren,Qiang Liu,Qing Wang,Dahu Wang

Nature communications 13:6497 PubMed36310237

2022

Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis.

Applications

Unspecified application

Species

Unspecified reactive species

Yoshiharu Muto,Eryn E Dixon,Yasuhiro Yoshimura,Haojia Wu,Kohei Omachi,Nicolas Ledru,Parker C Wilson,Andrew J King,N Eric Olson,Marvin G Gunawan,Jay J Kuo,Jennifer H Cox,Jeffrey H Miner,Stephen L Seliger,Owen M Woodward,Paul A Welling,Terry J Watnick,Benjamin D Humphreys

Nature communications 7:10060 PubMed26725982

2016

ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1.

Applications

Unspecified application

Species

Unspecified reactive species

Tomoya Yamaguchi,Can Lu,Lisa Ida,Kiyoshi Yanagisawa,Jiro Usukura,Jinglei Cheng,Naoe Hotta,Yukako Shimada,Hisanori Isomura,Motoshi Suzuki,Toyoshi Fujimoto,Takashi Takahashi
View all publications
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Product promise

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