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AB327120

Anti-ROR2 Antibody [CL5950]

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Mouse Monoclonal ROR2 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human ROR2.

View Alternative Names

NTRKR2, ROR2, Tyrosine-protein kinase transmembrane receptor ROR2

5 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ROR2 Antibody [CL5950] (AB327120)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ROR2 Antibody [CL5950] (AB327120)

Immunohistochemical staining of human placenta using ab327120 at 1 : 500–1 : 1000 dilution, showing membranous positivity in trophoblast.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ROR2 Antibody [CL5950] (AB327120)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ROR2 Antibody [CL5950] (AB327120)

Immunohistochemical staining of human small intestine using ab327120 at 1 : 500–1 : 1000 dilution, showing membranous positivity in glandular cells.

Immunocytochemistry/ Immunofluorescence - Anti-ROR2 Antibody [CL5950] (AB327120)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-ROR2 Antibody [CL5950] (AB327120)

Immunofluorescence staining of HeLa cells using ab327120 at 2–10 µg/ml, showing specific staining in the plasma membrane in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ROR2 Antibody [CL5950] (AB327120)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ROR2 Antibody [CL5950] (AB327120)

Immunohistochemical staining of human prostate using ab327120 at 1 : 500–1 : 1000 dilution, showing moderate membranous positivity in glandular cells as well as in smooth muscle cells.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ROR2 Antibody [CL5950] (AB327120)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ROR2 Antibody [CL5950] (AB327120)

Immunohistochemical staining of human skeletal muscle using ab327120 at 1 : 500–1 : 1000 dilution, showing absence of membranous positivity in skeletal muscle fibers as expected (negative control).

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

CL5950

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

ICC/IF, IHC-P

applications

Immunogen

Synthetic Peptide within Human ROR2.

Q01974

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500 - 1/1000", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "2-10 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed : 17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed : 25029443).
See full target information ROR2
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Product promise

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