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AB121143

Anti-RPGR antibody

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(1 Publication)

Rabbit Polyclonal RPGR antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human RPGR aa 350-550.

View Alternative Names

RP3, XLRP3, RPGR, X-linked retinitis pigmentosa GTPase regulator

4 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPGR antibody (AB121143)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPGR antibody (AB121143)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human fallopian tube tissue labelling RPGR with ab121143 at 1/50 dilution. Heat induced epitode retrieval was performed (pH 6).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPGR antibody (AB121143)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPGR antibody (AB121143)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human testis tissue labelling RPGR with ab121143 at 1/50 dilution. Heat induced epitode retrieval was performed (pH 6).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPGR antibody (AB121143)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPGR antibody (AB121143)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human liver tissue labelling RPGR with ab121143 at 1/50 dilution. Heat induced epitode retrieval was performed (pH 6).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPGR antibody (AB121143)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPGR antibody (AB121143)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human small intestine tissue labelling RPGR with ab121143 at 1/50 dilution. Heat induced epitode retrieval was performed (pH 6).

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human RPGR aa 350-550. The exact immunogen used to generate this antibody is proprietary information.

Q92834

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Acts as a guanine-nucleotide releasing factor (GEF) for RAB8A and RAB37 by promoting the conversion of inactive RAB-GDP to the active form RAB-GTP (PubMed : 20631154). GEF activity towards RAB8A may facilitate ciliary trafficking by modulating ciliary intracellular localization of RAB8A (PubMed : 20631154). GEF activity towards RAB37 maintains autophagic homeostasis and retinal function (By similarity). Involved in photoreceptor integrity (By similarity). May control cilia formation by regulating actin stress filaments and cell contractility. May be involved in microtubule organization and regulation of transport in primary cilia (PubMed : 21933838). May play a critical role in spermatogenesis and in intraflagellar transport processes (By similarity).
See full target information RPGR
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of neuroscience : the official journal of the Society for Neuroscience 37:3671-3685 PubMed28270572

2017

CREB Signaling Is Involved in Rett Syndrome Pathogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Qian Bu,Anxin Wang,Hamdi Hamzah,Alex Waldman,Keer Jiang,Qiping Dong,Ronghui Li,Jason Kim,Daniel Turner,Qiang Chang
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Product promise

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