Anti-RPL26L1 antibody [EPR8478]

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

RPL26L1 also known as ribosomal protein L26-like 1 is a protein that functions in the translation process within cells. This protein has a mass of approximately 17.4 kDa and is part of the ribosomal machinery specifically associated with the 60S ribosomal subunit. Expression of RPL26L1 is found in tissues with high protein synthesis demand including the liver and testis indicating its role in protein production.

Biological function summary

RPL26L1 acts as a component of the ribosome contributing to protein biosynthesis by facilitating the assembly of ribosomes and ensuring the synchronized translation of mRNA into polypeptides. RPL26L1 participates in forming a ribonucleoprotein complex essential for maintaining the structural stability of ribosomes during translation. This function is critical for efficient cell growth and protein expression.

Pathways

Ribosome-associated activities see RPL26L1 play a significant part in the mRNA translation pathway. Involvement in the translation initiation process links RPL26L1 closely with other ribosomal proteins such as RPL26 which is involved in regulating mRNA translation initiation and elongation. Together these proteins ensure the fidelity and efficiency of protein synthesis connecting RPL26L1 to the foundational processes of gene expression.

Associated diseases and disorders

Disruptions in RPL26L1 function can relate to conditions such as Diamond-Blackfan anemia a rare genetic disorder linked to faulty ribosomal proteins. In this context RPL26L1 interaction with proteins like RPS19 reflects its role in the pathology of diseases that originate from ribosomal protein malfunctions. Maintaining appropriate RPL26L1 function is essential for ribosomal integrity and overall cellular health.