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AB229534

Anti-RPL31 antibody

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(2 Publications)

Rabbit Polyclonal RPL31 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human 60S ribosomal protein L31.

View Alternative Names

Large ribosomal subunit protein eL31, 60S ribosomal protein L31, RPL31

1 Images
Western blot - Anti-RPL31 antibody (AB229534)
  • WB

Supplier Data

Western blot - Anti-RPL31 antibody (AB229534)

15% SDS-PAGE gel.

All lanes:

Western blot - Anti-RPL31 antibody (ab229534) at 1/1000 dilution

Lane 1:

HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extract at 30 µg

Lane 2:

A431 (human epidermoid carcinoma cell line) whole cell extract at 30 µg

Lane 3:

HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell extract at 30 µg

Lane 4:

HepG2 (human liver hepatocellular carcinoma cell line) whole cell extract at 30 µg

Predicted band size: 14 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human 60S ribosomal protein L31. The exact immunogen used to generate this antibody is proprietary information.

P62899

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chicken": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Xenopus laevis": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Zebrafish": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

RPL31 also known as Ribosomal Protein L31 is a component of the 60S subunit of the ribosome. This protein weighs approximately 14 kDa. It plays an important role in protein synthesis within the cell. RPL31 is widely expressed in many tissues including the liver kidney and lung. Its presence in these tissues indicates its importance in cellular function and metabolism.
Biological function summary

This ribosomal protein facilitates the assembly and stability of ribosomal structures enabling proper translation and protein synthesis. RPL31 is part of the larger ribosomal complex which includes multiple RNA molecules and many ribosomal proteins. It assists in maintaining the integrity of the ribosome during translation which is fundamental for efficient protein synthesis.

Pathways

RPL31 plays a role in the translation pathway and the ribosome biogenesis pathway. It interacts with other ribosomal proteins such as RPL17 and RPL26. These pathways are critical for cell growth and proliferation. RPL31's function within these pathways highlights its role in assembling ribosomal units and ensuring correct translation and protein production within cells.

RPL31 has been linked to Diamond-Blackfan anemia a rare blood disorder. This connection stems from its role in ribosomal structure and function. Mutations affecting RPL31 or related ribosomal proteins like RPS19 can disrupt normal ribosome biogenesis leading to disorders linked to defective erythropoiesis. Such findings emphasize the importance of RPL31 in maintaining normal cellular and hematopoietic function.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Component of the large ribosomal subunit (PubMed : 23636399, PubMed : 32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399, PubMed : 32669547).
See full target information 60S ribosomal protein L31
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Heliyon 9:e13076 PubMed36816257

2023

Ribosomal protein L31 (RPL31) inhibits the proliferation and migration of gastric cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Fang Wu,Yangyang Liu,Shenglin Hu,Canrong Lu

Cell death discovery 8:154 PubMed35379785

2022

Tumor suppressive role of microRNA-4731-5p in breast cancer through reduction of PAICS-induced FAK phosphorylation.

Applications

Unspecified application

Species

Unspecified reactive species

Lei Lang,Jing Tao,Chaomei Yang,Wei Li
View all publications
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Product promise

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