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AB236880

Anti-RPL38 antibody

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(1 Publication)

Rabbit Polyclonal RPL38 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human 60S ribosomal protein L38.

View Alternative Names

Large ribosomal subunit protein eL38, 60S ribosomal protein L38, RPL38

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-RPL38 antibody (AB236880)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-RPL38 antibody (AB236880)

HeLa (Human epithelial cell line from cervix adenocarcinoma) cells stained for RPL38 (Green) using ab236880 at a 1/100 dilution in ICC/IF. Secondary used is an Alexa-Fluor®488-conjugated Goat Anti-Rabbit IgG (H+L).

Western blot - Anti-RPL38 antibody (AB236880)
  • WB

Supplier Data

Western blot - Anti-RPL38 antibody (AB236880)

All lanes:

Western blot - Anti-RPL38 antibody (ab236880) at 1/1000 dilution

All lanes:

EC109 whole cell lysate

Secondary

All lanes:

Goat polyclonal to Rabbit IgG at 1/15000 dilution

Predicted band size: 8 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, ICC/IF

applications

Immunogen

Recombinant Full Length Protein corresponding to Human 60S ribosomal protein L38.

P63173

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cynomolgus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purity >95%.
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

RPL38 also known as Ribosomal Protein L38 is a component of the 60S subunit of ribosomes. It has a mass of approximately 9.4 kDa. You find this protein expressed in various tissues across the human body with higher expression in certain regions of the brain and reproductive organs. The primary role of RPL38 involves orchestrating the assembly and stabilization of ribosomal structures aiding in the translation of messenger RNA into proteins.
Biological function summary

The integration of RPL38 within the ribosomal complex is necessary for proper ribosome function. As a part of the large 60S ribosomal subunit RPL38 contributes to maintaining structural integrity and facilitating the catalytic process of peptide bond formation which is essential in protein synthesis. Ribosomal proteins including RPL38 collaborate to ensure fidelity and efficiency during the translation process.

Pathways

RPL38 influences critical cellular processes associated with mRNA translation and protein synthesis. Its role in the translational machinery links it to the broader pathway of protein biosynthesis. Additionally RPL38 aligns with the mTOR signaling pathway which oversees cell growth and proliferation. Within these pathways RPL38 cooperates with other ribosomal proteins and elements such as S6K1 and eIF4E contributing to the regulation of protein translation within cells.

RPL38 connects with several conditions through its involvement in protein synthesis. Abnormalities or mutations in RPL38 have associations with specific developmental disorders such as Diamond-Blackfan anemia a rare blood disorder. Furthermore disruptions in the function of ribosomal proteins like RPL38 also relate to cancer where dysfunctional protein synthesis can promote uncontrolled cell proliferation. The link between RPL38 and other ribosomal proteins like RPL5 and RPL11 is significant in understanding their combined contributions to these diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
See full target information 60S ribosomal protein L38
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

International journal of biological sciences 18:5168-5184 PubMed35982894

2022

Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation.

Applications

Unspecified application

Species

Unspecified reactive species

Yin Ni,Guo-Hua Wu,Juan-Juan Cai,Run Zhang,Yang Zheng,Jing-Quan Liu,Xiang-Hong Yang,Xue Yang,Ye Shen,Jun-Mei Lai,Xiang-Ming Ye,Shi-Jing Mo
View all publications
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