Goat Polyclonal RPRD2 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human RPRD2.
View Alternative Names
KIAA0460, HSPC099, RPRD2, Regulation of nuclear pre-mRNA domain-containing protein 2
- WB
Unknown
Western blot - Anti-RPRD2 antibody (AB10373)
ab10373 detection of human RPRD2 by Western blot. Samples : Whole cell lysate (WCL; amounts indicated) from HeLa cells. Antibody : ab10373 used at 1 μg/ml. Detection : Chemiluminescence with 3 minute exposure.
ab10373 detection of human RPRD2 by Western blot. Samples : Whole cell lysate (WCL; amounts indicated) from HeLa cells. Antibody : ab10373 used at 1 μg/ml. Detection : Chemiluminescence with 3 minute exposure.
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Western blot - Anti-RPRD2 antibody (ab10373)
Predicted band size: 156 kDa
false
Reactivity data
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Biological function summary
The regulatory activities of RPRD2 impact cellular processes through its part in multiple protein complexes particularly those focusing on transcription and RNA processing. RPRD2 collaborates with other proteins such as RPRD1A and RPRD1B to form a complex involved in mediating interactions with transcription factors and phosphatases. This complex functions in a coordinated manner to regulate the transcription machinery and contribute to RNA polymerase II activity modulation which in turn affects gene expression at a broader level.
Pathways
RPRD2 participates in several critical pathways including the RNA polymerase II transcription pathway and the mRNA maturation pathway. RPRD2's connection with the phosphatase complex places it in a network of interactions vital to maintaining transcriptional fidelity. Additionally RPRD2 is related to pathways involving proteins such as CDK9 which plays a role in controlling pause release at transcription start sites. These interactions position RPRD2 as an essential mediator within transcriptional networks.
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