Goat Polyclonal RPRD2 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human RPRD2 aa 1000-1050.
View Alternative Names
KIAA0460, HSPC099, RPRD2, Regulation of nuclear pre-mRNA domain-containing protein 2
- WB
Unknown
Western blot - Anti-RPRD2 antibody (AB17996)
Detection of Human RPRD2 by Western Blot.
Samples : Whole cell lysate (15 and 50 μg) from HEK293 cells.
Antibody : Affinity purified goat anti-RPRD2 antibody used at 1 and 0.4 mg/ml.
Detection : Chemiluminescence with an exposure time of 1 minute.
Lanes 1 - 2:
Western blot - Anti-RPRD2 antibody (ab17996) at 1 µg/mL
Lanes 3 - 4:
Western blot - Anti-RPRD2 antibody (ab17996) at 0.4 µg/mL
Lanes 1 and 3:
Whole cell lysate from HEK239 cells at 15 µg
Lanes 2 and 4:
Whole cell lysate from HEK239 cells at 50 µg
Predicted band size: 156 kDa
Observed band size: 225 kDa
false
Exposure time: 1min
Alternative Products
Complementary Products
Reactivity data
Properties and storage information
Form
Purification technique
Purification notes
Storage buffer
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The regulatory activities of RPRD2 impact cellular processes through its part in multiple protein complexes particularly those focusing on transcription and RNA processing. RPRD2 collaborates with other proteins such as RPRD1A and RPRD1B to form a complex involved in mediating interactions with transcription factors and phosphatases. This complex functions in a coordinated manner to regulate the transcription machinery and contribute to RNA polymerase II activity modulation which in turn affects gene expression at a broader level.
Pathways
RPRD2 participates in several critical pathways including the RNA polymerase II transcription pathway and the mRNA maturation pathway. RPRD2's connection with the phosphatase complex places it in a network of interactions vital to maintaining transcriptional fidelity. Additionally RPRD2 is related to pathways involving proteins such as CDK9 which plays a role in controlling pause release at transcription start sites. These interactions position RPRD2 as an essential mediator within transcriptional networks.
Product protocols
- Visit the General protocols
- Visit the Troubleshooting
Target data
Publications (1)
Recent publications for all applications. Explore the full list and refine your search
CNS neuroscience & therapeutics 31:e70279 PubMed39968701
2025
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com