JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB254638

Anti-RPS29 antibody

Be the first to review this product! Submit a review

|

(1 Publication)

Rabbit Polyclonal RPS29 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human 40S ribosomal protein S29 aa 1 to C-terminus.

View Alternative Names

Small ribosomal subunit protein uS14, 40S ribosomal protein S29, RPS29

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-RPS29 antibody (AB254638)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-RPS29 antibody (AB254638)

PFA fixed, Triton X-100 permeabilized A-431 (Human epidermoid carcinoma cell line) cells labeling RPS29 using ab254638 at 4µg/ml (green) in ICC/IF.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS29 antibody (AB254638)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS29 antibody (AB254638)

Paraffin-embedded human pancreas tissue stained for RPS29 using ab254638 at 1/1000 dilution in immunohistochemical analysis.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human 40S ribosomal protein S29 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P62273

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Pig": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

RPS29 also known as Ribosomal Protein S29 is a component of the small 40S subunit of the ribosome it weighs approximately 7.5 kDa. It plays a critical role in protein synthesis by facilitating mRNA decoding and peptidyl transferase activity. This protein is ubiquitously expressed in various tissues reflecting its essential role in cellular function.
Biological function summary

Ribosomal Protein S29 is part of the ribosomal complex which is important for cellular protein production. It ensures the proper translation of mRNA into amino acid sequences influencing protein assembly. RPS29 is not only vital for generating proteins but also contributes to the regulation of cell growth and proliferation through its participation in the ribosomal structure.

Pathways

The involvement of Ribosomal Protein S29 extends to the mTOR signaling pathway which regulates cell growth protein synthesis and autophagy. It is also part of the p53 pathway influencing cellular responses to stress and DNA damage. RPS29 works in conjunction with other ribosomal proteins like RPL11 and RPS6 which also have roles in these processes ensuring the fidelity and efficiency of protein synthesis in cells.

Abnormalities in Ribosomal Protein S29 are associated with Diamond-Blackfan Anemia a rare condition characterized by defective erythropoiesis. RPS29 mutations also implicate its relation to cancer development where disruptions in protein synthesis pathways can lead to tumorigenesis. The disorder connects RPS29 to other dysregulated proteins like p53 highlighting the impact of ribosomal dysfunction in disease progression.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Component of the small ribosomal subunit (PubMed : 23636399, PubMed : 25901680, PubMed : 25957688). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399, PubMed : 25901680, PubMed : 25957688).
See full target information 40S ribosomal protein S29
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in oncology 11:664369 PubMed34386416

2021

A Novel Tumor Suppressor Gene, ZNF24, Inhibits the Development of NSCLC by Inhibiting the WNT Signaling Pathway to Induce Cell Senescence.

Applications

Unspecified application

Species

Unspecified reactive species

Bo Pang,Yong Wang,Xiaoyan Chang
View all publications
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB254671

Anti-RPS25 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS25 antibody (AB254671)

  • 0
  • 0
Primary Antibodies

AB88496

Anti-RIOK1/RIO1 antibody

Immunoprecipitation - Anti-RIOK1/RIO1 antibody (AB88496)

  • 3
  • 1
Primary Antibodies

AB254670

Anti-RPS21 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS21 antibody (AB254670)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com