AB230862

Anti-RPS7 antibody

Name: Anti-RPS7 antibody (ab230862) | Abcam
Brand: Abcam Limited
SKU: AB230862
Price: 605 USD
Availability: InStock

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(2 Publications)

Rabbit Polyclonal RPS7 antibody. Suitable for WB, IHC-P and reacts with Human, Mouse, Rat samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human RPS7.

View Alternative Names

Small ribosomal subunit protein eS7, 40S ribosomal protein S7, RPS7

3 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS7 antibody (AB230862)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS7 antibody (AB230862)

Formalin-fixed, paraffin-embedded human small intestine tissue stained for RPS7 with Immunohistochemistry at 1/50 dilution in immunohistochemical analysis.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS7 antibody (AB230862)

Formalin-fixed, paraffin-embedded human cerebellum tissue stained for RPS7 with Immunohistochemistry at 1/50 dilution in immunohistochemical analysis.

Supplier Data

Western blot - Anti-RPS7 antibody (AB230862)

All lanes:

Western blot - Anti-RPS7 antibody (ab230862) at 1/500 dilution

Lane 1:

HeLa (human epithelial cell line from cervix adenocarcinoma) cell extract

Lane 2:

NIH/3T3 (mouse embryo fibroblast cell line) cell extract

Lane 3:

SW480 (human colorectal adenocarcinoma cell line) cell extract

Lane 4:

MCF7 (human breast adenocarcinoma cell line) cell extract

Lane 5:

A549 (human lung carcinoma cell line) cell extract

Lane 6:

Mouse liver extract

Lane 7:

Rat liver extract

Predicted band size: 22 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human RPS7.

P62081

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Zebrafish": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification

Storage buffer

pH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

RPS7 also known as Ribosomal Protein S7 plays an important role in protein synthesis as a component of the ribosome. It is a structural protein with a mass of approximately 22 kDa and is expressed ubiquitously across different tissues. Within the ribosome RPS7 belongs to the small 40S subunit where it works alongside other ribosomal proteins and rRNA to contribute to the assembly and function of the ribosome during translation.

Biological function summary

RPS7 facilitates the translation process by stabilizing rRNA and ensuring correct assembly of the ribosomal subunits. As one of the ribosomal proteins it is essential for maintaining ribosome integrity and function within the ribosomal complex. Through interactions with rRNA and other ribosomal proteins RPS7 aids in the translational accuracy and efficiency ultimately influencing protein synthesis rates in cells.

Pathways

RPS7 participates importantly in the translation machinery within cells. It forms part of the ribosome which serves as a central platform for the mRNA translation pathway. As an integral component of ribosomal pathways RPS7 interacts with other key proteins like RPL and EIF families which assist in translation initiation elongation and termination processes. The involvement of RPS7 in these pathways supports cellular protein homeostasis and gene expression regulation.

RPS7 has been linked to Diamond-Blackfan anemia a condition characterized by defective ribosomal protein production leading to bone marrow failure. Mutations in RPS7 and similar ribosomal proteins such as RPS19 impact ribosome biogenesis disrupting normal erythropoiesis and causing anemia. Additionally upregulation of RPS7 has been observed in some cancers where altered protein synthesis contributes to tumorigenesis and tumor growth.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Component of the small ribosomal subunit (PubMed : 23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399). Required for rRNA maturation (PubMed : 19061985). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed : 34516797).

See full target information RPS7

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Molecular & cellular proteomics : MCP 21:100273 PubMed35918030

2022

Quantitative Proteomics Identifies Proteins Enriched in Large and Small Extracellular Vesicles.

Applications

Unspecified application

Species

Unspecified reactive species

Anna Lischnig,Markus Bergqvist,Takahiro Ochiya,Cecilia Lässer

Oncology letters 21:331 PubMed33692863

2021

Altered expression of striatin-4 is associated with poor prognosis in bladder transitional cell carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yuhan Zhang,Xinquan Gu,Fuquan Jiang,Pinghui Sun,Xu Li

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-RPS7 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS7 antibody (AB230862)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS7 antibody (AB230862)

Western blot - Anti-RPS7 antibody (AB230862)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Complementary Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (2)

Product promise