AB157125

Anti-RPS9 antibody

Name: Anti-RPS9 antibody (ab157125) | Abcam
Brand: Abcam Limited
SKU: AB157125
Price: 510 USD
Availability: InStock

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(1 Publication)

Rabbit Polyclonal RPS9 antibody. Suitable for WB and reacts with Human, Mouse samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human 40S ribosomal protein S9 aa 1-50.

View Alternative Names

Small ribosomal subunit protein uS4, 40S ribosomal protein S9, RPS9

1 Images

Unknown

Western blot - Anti-RPS9 antibody (AB157125)

All lanes:

Western blot - Anti-RPS9 antibody (ab157125) at 0.4 µg/mL

Lane 1:

HeLa whole cell lysate at 50 µg

Lane 2:

HeLa whole cell lysate at 15 µg

Lane 3:

293T whole cell lysate at 50 µg

Lane 4:

Jurkat whole cell lysate at 50 µg

Lane 5:

NIH 3T3 whole cell lysate at 50 µg

Predicted band size: 23 kDa

true

Exposure time: 30s

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human, Mouse

Applications

applications

Immunogen

Synthetic Peptide within Human 40S ribosomal protein S9 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

P46781

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chinese hamster": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Common marmoset": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Fish": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Guinea pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Horse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Lizard": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rabbit": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Zebra finch": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

ab157125 is affinity purified using an epitope specific to RPS9 immobilized on solid support.

Storage buffer

pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

RPS9 also known as Ribosomal Protein S9 plays an important role in protein synthesis by being part of the small 40S ribosomal subunit. It has a molecular mass of approximately 22 kDa. This protein is expressed in various tissues throughout the body and is essential for ribosome function. Its primary mechanical function involves the formation of ribosomes which are key components in the translation process translating the genetic code into proteins.

Biological function summary

As a component of the ribosomal assembly RPS9 is essential for maintaining the structure and function of ribosomes. It forms a part of the ribonucleoprotein complex that ensures the fidelity and accuracy of mRNA translation during protein synthesis. This activity is vital for cell growth and proliferation as it directly influences protein production efficiency. Any disruptions in this process can lead to misfolded proteins or incomplete translations affecting cell functionality.

Pathways

The function of RPS9 is critical in the mRNA processing and translation pathways. It associates closely with other ribosomal proteins such as RPS3 and RPL11 participating in the synthesis and processing of proteins required for various cellular activities. This involvement impacts key pathways like the mTOR signaling pathway which controls cell growth and metabolism and the p53 signaling pathway which is involved in cell cycle regulation and stress responses.

The role of RPS9 implicates it in cancer and Diamond-Blackfan anemia. Mutations or dysregulation of RPS9 can lead to abnormal cell proliferation contributing to oncogenesis. RPS9 has connections with the p53 protein pathway which plays a significant role in tumorigenesis when mutated or impaired. In Diamond-Blackfan anemia defects in ribosomal protein function including that of RPS9 result in bone marrow failure and defective erythropoiesis affecting red blood cell production.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
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Target data

Component of the small ribosomal subunit (PubMed : 23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed : 34516797).

See full target information 40S ribosomal protein S9

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cancer science 114:1464-1478 PubMed36601865

2023

Downregulated mitochondrial transcription factor A enhances mycoplasma infection to promote the metastasis of hepatocellular carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yinping Wang,Gang Wang,Xin Hong,Jing Zhao,Dan Wu,Lin Chen,Xiaoli Liu,Deyu Kong,Qichao Huang,Jinliang Xing,Nan Wang,Yilin Zhao

View all publications

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Product promise

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For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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Anti-RPS9 antibody

Western blot - Anti-RPS9 antibody (AB157125)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Alternative Products

Primary Antibodies

Complementary Products

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

Product promise