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AB21207

Anti-Rubella Virions antibody

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(1 Publication)

Goat Polyclonal Rubella Virions antibody. Suitable for ELISA, ICC/IF, FuncS (Neut/Block) and reacts with Rubella virus samples. Cited in 1 publication. Immunogen corresponding to Virus preparation containing Rubella Virions protein.

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Rubella virus

Applications

FuncS (Neut/Block), ELISA, ICC/IF

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

Negative against VERO cells by direct immunofluorescence.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "FuncSNeutBlock" : {"fullname" : "Functional Studies (Neut/Block)", "shortname":"FuncS (Neut/Block)"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rubella virus": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>", "FuncSNeutBlock-species-checked": "guaranteed", "FuncSNeutBlock-species-dilution-info": "", "FuncSNeutBlock-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Ion exchange chromatography
Purification notes
>95% pure. Sodium sulfate precipitation and ion-exchange chromatography.
Storage buffer
Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Rubella virions also known as rubella virus particles are spherical and enveloped entities with an average diameter of 50-70 nm. These virions are composed mainly of three structural proteins: the capsid protein and the envelope glycoproteins E1 and E2. Within the host cell rubella virions replicate in the cytoplasm of infected epithelial cells. Their envelope derives from the host cell membrane highlighting their interaction with the infected host during budding.
Biological function summary

Rubella virions serve as the infectious agents responsible for the transmission of rubella which is a contagious disease characterized by rash and fever. As individual units rubella virions do not form part of a complex with other viruses but require assembly via interactions among the capsid protein and envelope glycoproteins. The virion structure plays a central role in facilitating host cell receptor binding and membrane fusion which allows the virus to deliver its RNA genome into host cells for replication.

Pathways

Viral entry and replication mechanisms drive the activities of rubella virions. The virions exploit the endocytic pathway to enter host cells a process that is important for initiating infection. During replication non-structural proteins facilitate the synthesis of viral components. Important proteins in these processes include the E1 glycoprotein which is involved in receptor interaction and membrane fusion an integral part of the virion's infection cycle.

Rubella virions are primarily linked to rubella infection also known as German measles and congenital rubella syndrome. This viral infection triggers an immune response in the host involving cytokines and antibodies notably the anti-rubella antibody which helps clear the virus. Congenital rubella syndrome occurs when maternal infection during pregnancy results in significant developmental anomalies in the fetus. This association highlights the importance of monitoring and vaccination efforts to prevent these serious conditions.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information Rubella Virions
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

iScience 28:112988 PubMed41054545

2025

Multiregional single-cell transcriptomics reveals an association between partial EMT and immunosuppressive states in oral squamous cell carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Seunghoon Kim,Hyun Jung Kee,Dahee Kim,Jinho Jang,Hyoung-Oh Jeong,Nam Suk Sim,Mischa Selig,Jana Ihlow,Livius Penter,Taejoo Hwang,David Whee-Young Choi,Kyoung Jun Lee,Jaewoong Lee,Young Min Park,Semin Lee,Yoon Woo Koh
View all publications
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Product promise

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