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AB204073

Anti-RWDD4A antibody

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(1 Publication)

Rabbit Polyclonal RWDD4A antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human RWDD4 aa 50 to C-terminus.

View Alternative Names

FAM28A, RWDD4A, RWDD4, RWD domain-containing protein 4, Protein FAM28A

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RWDD4A antibody (AB204073)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RWDD4A antibody (AB204073)

Immunohistochemical analysis of paraffin-embedded Human cerebellum tissue, labeling RWDD4A with ab204073 at 1/50 dilution.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human RWDD4 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q6NW29

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

RWDD4A also known as RWD domain containing 4A is a protein involved in regulating protein interactions. This protein weighs approximately 19 kDa. It is expressed widely in human tissues with significant expression in the brain liver and kidney. RWDD4A interacts with other proteins through its RWD domain facilitating specific binding and signaling processes within cells.
Biological function summary

The protein acts as a modulator in diverse cellular functions such as signal transduction and cellular communication. It often forms part of larger protein complexes that assist in finely tuning these processes. RWDD4A serves a role in the regulation of certain pathways by interacting with other proteins and influencing their activity consequently affecting cellular responses.

Pathways

RWDD4A plays a role in major biological pathways like the MAPK signaling pathway. Through these pathways RWDD4A influences cell proliferation and stress responses. It interacts with proteins such as MAPKs themselves which are important for transmitting signals from extracellular stimuli to the cellular interior directing various physiological effects.

RWDD4A associates with conditions like neurodegenerative diseases and liver fibrosis. Alterations in RWDD4A function or expression might disrupt normal signaling pathways linking it to these disorders. It shares connections with proteins such as TGF-beta in liver fibrosis impacting tissue repair processes and contributing to disease pathogenesis.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information RWDD4
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Functional & integrative genomics 24:38 PubMed38376551

2024

DKC1 aggravates gastric cancer cell migration and invasion through up-regulating the expression of TNFAIP6.

Applications

Unspecified application

Species

Unspecified reactive species

Huihua Chen,Yibo Wu,Yancheng Jiang,Zixuan Chen,Tingjin Zheng
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