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Rabbit Polyclonal RWDD4A antibody. Suitable for IHC-P and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human RWDD4 aa 50 to C-terminus.

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Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RWDD4A antibody (AB204073), expandable thumbnail

Key facts

Isotype

IgG

Host species

Rabbit

Storage buffer

pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)

Form

Liquid

Clonality

Polyclonal

Immunogen

  • Recombinant Fragment Protein within Human RWDD4 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q6NW29

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
IHC-P
Human
Tested
Mouse
Predicted

Tested
Tested

Species

Human

Dilution info

1/50.00000 - 1/200.00000

Notes

Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Predicted
Predicted

Species

Mouse

Dilution info

-

Notes

-

Alternative names

Recommended products

Rabbit Polyclonal RWDD4A antibody. Suitable for IHC-P and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human RWDD4 aa 50 to C-terminus.

Key facts

Isotype

IgG

Form

Liquid

Clonality

Polyclonal

Immunogen
  • Recombinant Fragment Protein within Human RWDD4 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q6NW29
Purification technique

Affinity purification Immunogen

Concentration
Loading...

Storage

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

RWDD4A also known as RWD domain containing 4A is a protein involved in regulating protein interactions. This protein weighs approximately 19 kDa. It is expressed widely in human tissues with significant expression in the brain liver and kidney. RWDD4A interacts with other proteins through its RWD domain facilitating specific binding and signaling processes within cells.

Biological function summary

The protein acts as a modulator in diverse cellular functions such as signal transduction and cellular communication. It often forms part of larger protein complexes that assist in finely tuning these processes. RWDD4A serves a role in the regulation of certain pathways by interacting with other proteins and influencing their activity consequently affecting cellular responses.

Pathways

RWDD4A plays a role in major biological pathways like the MAPK signaling pathway. Through these pathways RWDD4A influences cell proliferation and stress responses. It interacts with proteins such as MAPKs themselves which are important for transmitting signals from extracellular stimuli to the cellular interior directing various physiological effects.

Associated diseases and disorders

RWDD4A associates with conditions like neurodegenerative diseases and liver fibrosis. Alterations in RWDD4A function or expression might disrupt normal signaling pathways linking it to these disorders. It shares connections with proteins such as TGF-beta in liver fibrosis impacting tissue repair processes and contributing to disease pathogenesis.

Product promise

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1 product image

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RWDD4A antibody (ab204073), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RWDD4A antibody (ab204073)

    Immunohistochemical analysis of paraffin-embedded Human cerebellum tissue, labeling RWDD4A with ab204073 at 1/50 dilution.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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