Goat Polyclonal S Opsin/BCP antibody. Suitable for IHC-P and reacts with Mouse samples. Cited in 4 publications.
View Alternative Names
Bcp, Opn1sw, Short-wave-sensitive opsin 1, S opsin, Blue cone photoreceptor pigment, Blue-sensitive opsin, Short wavelength-sensitive cone opsin, BOP
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S Opsin/BCP antibody (AB235274)
Formalin-fixed, paraffin-embedded mouse eye tissue stained for S Opsin/BCP using ab235274 at a 1/100 dilution (30mins at RT) followed by a donkey anti-goat (HRP) secondary at 4μl/ml (20mins at RT).
Panel A : Mouse retina H&E.
Panel B : ab235274, 20X magnification.
Panel C : ab235274, 40X magnification.
Reactivity data
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Supplementary information
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Biological function summary
S Opsin functions as a light-sensitive receptor involved in photoreception. It is part of the visual system complex interacting with other opsins such as L and M opsins which are sensitive to different wavelengths. Upon light activation S Opsin undergoes a conformational change which initiates a cascade of biochemical events leading to the hyperpolarization of cone cells. These signals transmit visual information from the retina to the brain contributing to color differentiation and visual acuity.
Pathways
S Opsin is integral to the phototransduction pathway an important process that converts light into electrical signals. This pathway involves various proteins including transducin a G-protein that interacts with opsins to propagate the signal initiated by light activation. Further along in the pathway phosphodiesterase acts to amplify the signal within the photoreceptor cells. The effective interaction of these proteins ensures the accurate transmission of visual information under different lighting conditions.
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Target data
Publications (4)
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Journal of nanobiotechnology 23:575 PubMed40830790
2025
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Translational vision science & technology 14:14 PubMed40354066
2025
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Unspecified reactive species
Human molecular genetics 33:1916-1928 PubMed39231530
2024
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Unspecified reactive species
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11:e2401939 PubMed38704700
2024
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