Rabbit Polyclonal S100A16 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human S100A16 aa 50 to C-terminus.
View Alternative Names
S100F, AAG13, S100A16, Protein S100-A16, Aging-associated gene 13 protein, Protein S100-F, S100 calcium-binding protein A16
- IP
Supplier Data
Immunoprecipitation - Anti-S100A16 antibody (AB240572)
S100A16 was immunoprecipitated from HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) prepared using NETN lysis buffer using ab240572 at 20 μl/reaction. Western blot of the immunoprecipitates was performed using ab240572 at 1/100 dilution.
Lane 1 : ab240572 IP in HeLa whole cell lysate
Lane 2 : Control IgG IP in HeLa whole cell lysate.
Chemiluminescence detection : 30 seconds.
All lanes:
Immunoprecipitation - Anti-S100A16 antibody (ab240572)
Predicted band size: 11 kDa
false
- WB
Supplier Data
Western blot - Anti-S100A16 antibody (AB240572)
Lysates prepared using NETN lysis buffer.
All lanes:
Western blot - Anti-S100A16 antibody (ab240572) at 1/1000 dilution
Lane 1:
HeLa (Human epithelial cell line from cervix adenocarcinoma) whole cell lysate at 50 µg
Lane 2:
HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate at 50 µg
Lane 3:
Jurkat (Human T cell leukemia cell line from peripheral blood) whole cell lysate at 50 µg
Predicted band size: 11 kDa
false
Exposure time: 30s
Alternative Products
Complementary Products
Reactivity data
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Supplementary information
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Biological function summary
S100A16 is involved in cellular processes such as proliferation differentiation and migration. It participates in the modulation of cytoskeletal dynamics and cell cycle regulation. S100A16 often integrates into multiprotein complexes where it interacts with target proteins to exert its biological effects. Studies show that S100A16 may also contribute to epithelial-mesenchymal transition (EMT) an important event in development and cancer progression.
Pathways
S100A16 functions in signaling pathways linked to calcium-dependent processes. In the MAPK signaling pathway it interacts with proteins like ERK1/2 to regulate cell proliferation and survival. Furthermore S100A16 is also associated with the TGF-beta pathway where its role in EMT becomes significant and involves interactions with TGF-beta-related factors. These pathways underline the importance of S100A16 in cellular homeostasis and developmental processes.
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Target data
Publications (2)
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Molecular medicine reports 31: PubMed39450567
2024
Applications
Unspecified application
Species
Unspecified reactive species
Cell reports 33:108264 PubMed33053349
2020
Applications
Unspecified application
Species
Unspecified reactive species
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