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AB203689

Anti-S100P binding protein antibody

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Rabbit Polyclonal S100P binding protein antibody. Suitable for IHC-P and reacts with Mouse samples. Immunogen corresponding to Synthetic Peptide within Human S100PBP aa 350 to C-terminus conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

S100PBPR, S100PBP, S100P-binding protein, S100P-binding protein Riken

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100P binding protein antibody (AB203689)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100P binding protein antibody (AB203689)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Mouse spleen tissue labeling S100P binding protein with ab203689 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human S100PBP aa 350 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q96BU1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100.00000 - 1/500.00000", "IHCP-species-notes": "<p></p>" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The S100P binding protein also called S100PB interacts directly with S100P a member of the S100 family of calcium-binding proteins. This protein has a molecular mass of approximately 40 kDa. It is present in various tissues and organs including the placenta and certain types of epithelial tissues. The protein's expression varies and changes in its expression levels often correlate with different physiological and pathological conditions.
Biological function summary

S100PB modulates the activity of S100P by binding to it which influences several cellular functions. It does not function as a standalone protein but is instead part of complexes that affect cellular signaling proliferation and differentiation. This interaction can impact cellular processes such as cell growth and apoptosis hinting at roles in cellular proliferation mechanisms and stress responses.

Pathways

The S100P binding protein is associated with the regulation of cellular responses to external stressors and intracellular signal transduction pathways. It plays a role in the MAPK/ERK pathway and might influence the activity of proteins like Raf and MEK. These pathways are critical for intracellular communication that controls cell division differentiation and development. The protein interactions and binding activities show its significance within these cellular signaling frameworks.

S100P binding protein involvement has been noted in cancer progression and metastasis as well as inflammatory diseases. In cancer it interacts with and possibly regulates other S100 proteins contributing to processes that facilitate tumor growth and spread. Its role in inflammation may include modulating inflammatory responses linked to the activities of proteins involved in immune regulation. The connection with these disorders makes it a potential target for therapeutic interventions given its influence on cellular signaling and disease-related pathways.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information S100PBP
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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