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AB92350

Anti-SCGB3A1 antibody

5

(1 Review)

|

(1 Publication)

Goat Polyclonal SCGB3A1 antibody. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human SCGB3A1 aa 50-100.

View Alternative Names

HIN1, PNSP2, UGRP2, UNQ629/PRO1245, SCGB3A1, Secretoglobin family 3A member 1, Cytokine HIN-1, High in normal 1, Pneumo secretory protein 2, Uteroglobin-related protein 2, PnSP-2

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Applications

WB

applications

Immunogen

Synthetic Peptide within Human SCGB3A1 aa 50-100. The exact immunogen used to generate this antibody is proprietary information.

Q96QR1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab92350 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Storage buffer
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 0.5% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

SCGB3A1 also known as Secretoglobin Family 3A Member 1 or Uteroglobin-Related Protein 1 is a small secretory protein with a molecular mass of approximately 10 kDa. It is mainly expressed in non-ciliated epithelial cells of the respiratory tract and also found in the prostate uterus and mammary gland tissues. The protein belongs to the secretoglobin family which is a group of small cysteine-rich secretory proteins known for their involvement in complex biological processes.
Biological function summary

SCGB3A1 has important roles in modulating immune response and maintaining epithelial integrity. It acts as a secreted cytokine with some anti-inflammatory properties influencing the immune cell activity and reducing inflammation. Although SCGB3A1 does not form a known complex with other proteins its function in tissue regulation indicates a significant impact on the local immune environment making it a point of interest in respiratory and reproductive health.

Pathways

The function of SCGB3A1 reflects its involvement in the immune signaling pathway particularly in response to inflammatory cytokines. The protein is part of a network interacting with various immune regulatory pathways including the interleukin signaling pathway. SCGB3A1 achieves this through interactions with proteins such as IL-10 which plays an important role in balancing pro-inflammatory and anti-inflammatory responses.

SCGB3A1 has associations with conditions such as asthma and chronic obstructive pulmonary disease (COPD). Its anti-inflammatory functions may impact the severity and progression of these respiratory illnesses. Research links SCGB3A1 to IL-13 in the context of asthma highlighting its part in modulating the immune response within the lung tissue. This connection makes SCGB3A1 a potential target for therapeutic exploration in respiratory diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Secreted cytokine-like protein. Inhibits cell growth in vitro.
See full target information SCGB3A1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of extracellular vesicles 13:e70012 PubMed39508411

2024

PlexinA1 (PLXNA1) as a novel scaffold protein for the engineering of extracellular vesicles.

Applications

Unspecified application

Species

Unspecified reactive species

Hang Zhao,Zhi Li,Da Liu,Jiaxun Zhang,Zhicheng You,Yuzhang Shao,Hongyan Li,Jun Yang,Xiang Liu,Miaozhu Wang,Chengen Wu,Jing Chen,Jianwu Wang,Guanyi Kong,Libo Zhao
View all publications
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Product promise

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