Rabbit Polyclonal SEC31B antibody. Suitable for WB, IHC-P and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human SEC31B.
Constituents: Whole serum
| WB | IHC-P | |
|---|---|---|
| Human | Expected | Expected |
| Mouse | Predicted | Predicted |
| Rat | Predicted | Predicted |
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info Use at an assay dependent concentration. | Notes - |
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat | Dilution info - | Notes - |
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info Use at an assay dependent concentration. | Notes - |
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat | Dilution info - | Notes - |
As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum.
SEC31L2, SEC31B, Protein transport protein Sec31B, SEC31-like protein 2, SEC31-related protein B, SEC31B-1
Rabbit Polyclonal SEC31B antibody. Suitable for WB, IHC-P and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human SEC31B.
Constituents: Whole serum
This antibody reacts specifically with human 128 kDa SEC31B protein.
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SEC31B sometimes referred to as SEC31 homolog B is a protein that functions mechanically in vesicle formation. It is a component of the coat protein complex II (COPII) which is essential for the transport of proteins from the endoplasmic reticulum to the Golgi apparatus. SEC31B has an approximate mass of 134 kDa. This protein is expressed in various tissues with notable levels observed in pancreatic and muscle tissues.
SEC31B is part of the COPII complex that operates in mediating vesicle budding and cargo selection during protein transport. Its activity is essential for maintaining the proper flow of proteins through the secretory pathway which is an integral part of cellular homeostasis. As a component of the COPII complex SEC31B interacts closely with other proteins such as SEC23 to ensure efficient vesicle transportation and regulation.
SEC31B participates in the secretory pathway and endoplasmic reticulum-to-Golgi transport. This process is vital for protein processing and trafficking within the cell. The protein works closely with SEC13 another COPII complex component to facilitate vesicle formation and transport highlighting its role in maintaining cellular function and organization.
SEC31B has been associated with pancreatic disorders particularly affecting protein trafficking. Its interaction with the SEC23 protein has implications in these conditions suggesting disruptions in vesicular transport could lead to disease. Additionally research investigates potential links between SEC31B and muscular disorders although the exact mechanisms remain under study. Understanding SEC31B's role might provide insights into therapeutic targets for these diseases.
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This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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