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AB80053

Anti-SEC31B antibody

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(1 Publication)

Rabbit Polyclonal SEC31B antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human SEC31B.

View Alternative Names

SEC31L2, SEC31B, Protein transport protein Sec31B, SEC31-like protein 2, SEC31-related protein B, SEC31B-1

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Synthetic Peptide within Human SEC31B. The exact immunogen used to generate this antibody is proprietary information.

Q9NQW1

Specificity

This antibody reacts specifically with human 128 kDa SEC31B protein.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purity
Whole antiserum
Storage buffer
Constituents: Whole serum
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

SEC31B sometimes referred to as SEC31 homolog B is a protein that functions mechanically in vesicle formation. It is a component of the coat protein complex II (COPII) which is essential for the transport of proteins from the endoplasmic reticulum to the Golgi apparatus. SEC31B has an approximate mass of 134 kDa. This protein is expressed in various tissues with notable levels observed in pancreatic and muscle tissues.
Biological function summary

SEC31B is part of the COPII complex that operates in mediating vesicle budding and cargo selection during protein transport. Its activity is essential for maintaining the proper flow of proteins through the secretory pathway which is an integral part of cellular homeostasis. As a component of the COPII complex SEC31B interacts closely with other proteins such as SEC23 to ensure efficient vesicle transportation and regulation.

Pathways

SEC31B participates in the secretory pathway and endoplasmic reticulum-to-Golgi transport. This process is vital for protein processing and trafficking within the cell. The protein works closely with SEC13 another COPII complex component to facilitate vesicle formation and transport highlighting its role in maintaining cellular function and organization.

SEC31B has been associated with pancreatic disorders particularly affecting protein trafficking. Its interaction with the SEC23 protein has implications in these conditions suggesting disruptions in vesicular transport could lead to disease. Additionally research investigates potential links between SEC31B and muscular disorders although the exact mechanisms remain under study. Understanding SEC31B's role might provide insights into therapeutic targets for these diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum.
See full target information SEC31B
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Stem cell research & therapy 9:30 PubMed29402309

2018

Embryonic stem cell-derived cardiomyocytes for the treatment of doxorubicin-induced cardiomyopathy.

Applications

Unspecified application

Species

Unspecified reactive species

Danúbia Silva Dos Santos,Guilherme Visconde Brasil,Isalira Peroba Rezende Ramos,Fernanda Cristina Paccola Mesquita,Tais Hanae Kasai-Brunswick,Michelle Lopes Araújo Christie,Gustavo Monnerat Cahli,Raiana Andrade Quintanilha Barbosa,Sandro Torrentes da Cunha,Jonathas Xavier Pereira,Emiliano Medei,Antonio Carlos Campos de Carvalho,Adriana Bastos Carvalho,Regina Coeli Dos Santos Goldenberg
View all publications
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Product promise

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