Anti-SEZ6L antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

SEZ6L serves important roles in synaptic function and neuronal connectivity. The protein participates in synapse formation by interacting with other cell adhesion molecules. SEZ6L also influences dendritic growth affecting the brain's ability to form and maintain neural circuits. It does not typically integrate into large protein complexes functioning instead as part of dynamic networks with specific partners in synaptic regions.

Pathways

SEZ6L engages in signaling cascades vital to neurodevelopment and synapse maintenance. In the MAPK/ERK pathway it interacts with proteins that facilitate neuronal proliferation and differentiation. SEZ6L is also involved in the neurotrophic receptor signaling pathway where it collaborates with proteins such as NTRK2 to enhance neuronal survival and plasticity. These interactions highlight its significant role in maintaining normal brain function.