JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB234144

Anti-Siglec 7 antibody [6-434]

Be the first to review this product! Submit a review

|

(1 Publication)

Mouse Monoclonal Siglec 7 antibody. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing SIGLEC7 protein.

View Alternative Names

CD328, AIRM1, SIGLEC7, Sialic acid-binding Ig-like lectin 7, Siglec-7, Adhesion inhibitory receptor molecule 1, CDw328, D-siglec, QA79 membrane protein, p75, AIRM-1

1 Images
Flow Cytometry - Anti-Siglec 7 antibody [6-434] (AB234144)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-Siglec 7 antibody [6-434] (AB234144)

Surface staining of Siglec 7 in human peripheral blood cells with ab234144. Gated on leukocytes.

  • 578 PE

    PE Anti-Siglec 7 antibody [6-434]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

6-434

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing SIGLEC7 protein. The exact immunogen used to generate this antibody is proprietary information.

Q9Y286

style
left-column

Alternative Products

Primary Antibodies

AB111619

Anti-Siglec 7 antibody

Immunocytochemistry/ Immunofluorescence - Anti-Siglec 7 antibody (AB111619)

  • 0
  • 0
Primary Antibodies

AB243643

Anti-Siglec 7 antibody [EPR23118-130]

RabMAb|Recombinant

Flow Cytometry - Anti-Siglec 7 antibody [EPR23118-130] (AB243643)

  • 0
  • 0
Primary Antibodies

AB267396

Anti-Siglec 7 antibody [EPR23118-130] - BSA and Azide free

RabMAb|Recombinant

Flow Cytometry - Anti-Siglec 7 antibody [EPR23118-130] - BSA and Azide free (AB267396)

  • 0
  • 0
Primary Antibodies

AB133388

Anti-Siglec 7 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Siglec 7 antibody (AB133388)

  • 0
  • 0

Complementary Products

Assay Kits

AB267615

Human Siglec 7 ELISA Kit

Sandwich ELISA - Human Siglec 7 ELISA Kit (AB267615)

  • 0
  • 0
Primary Antibodies

AB197981

Anti-SIGLEC9 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SIGLEC9 antibody (AB197981)

  • 0
  • 0
Secondary Antibodies

AB125912

Rabbit monoclonal [H26-10] Anti-Human IgG1 H&L

RabMAb|Recombinant

ELISA - Rabbit monoclonal [H26-10] Anti-Human IgG1 H&L (AB125912)

  • 0
  • 0
Primary Antibodies

AB243658

Anti-SLAMF6 antibody [EPR23122-130]

RabMAb|Recombinant|Trial Size

Immunocytochemistry/ Immunofluorescence - Anti-SLAMF6 antibody [EPR23122-130] (AB243658)

  • 0
  • 0
Primary Antibodies

AB245735

Anti-Sialoadhesin/CD169 antibody [SP213] - BSA and Azide free

BOND RX™ Validated|RabMAb|Advanced Validation|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sialoadhesin/CD169 antibody [SP213] - BSA and Azide free (AB245735)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1-4 µg/mL", "FlowCyt-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Purification notes
Purity is > 95% by SDS-PAGE.
Storage buffer
pH: 7.4 Preservative: 0.0975% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
See full target information SIGLEC7
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature nanotechnology 19:1224-1233 PubMed38802667

2024

Virus-like structures for combination antigen protein mRNA vaccination.

Applications

Unspecified application

Species

Unspecified reactive species

Jingjing Zhang,Yanmei Li,Fengyuan Zeng,Changyong Mu,Change Liu,Lichun Wang,Xiaowu Peng,Liping He,Yanrui Su,Hongbing Li,An Wang,Lin Feng,Dongxiu Gao,Zhixiao Zhang,Gang Xu,Yixuan Wang,Rong Yue,Junbo Si,Lichun Zheng,Xiong Zhang,Fuyun He,Hongkun Yi,Zhongshu Tang,Gaocan Li,Kaili Ma,Qihan Li
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com