JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB190267

Anti-SIX6OS1 antibody

Be the first to review this product! Submit a review

|

(0 Publication)

Rabbit Polyclonal SIX6OS1 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human SIX6OS1 aa 200-300.

View Alternative Names

C14orf39, SIX6OS1, Protein SIX6OS1, Six6 opposite strand transcript 1

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-SIX6OS1 antibody (AB190267)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-SIX6OS1 antibody (AB190267)

Immunocytochemical analysis of RT4 (Human urinary bladder cancer cell line) whole cells labeling SIX6OS1 in the nucleus and nucleoli with ab190267 at 2 μg/ml.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SIX6OS1 antibody (AB190267)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SIX6OS1 antibody (AB190267)

Immunohistochemical analysis of human testis tissue labeling SIX6OS1 in nucleus of cells in seminiferus ducts with ab190267 at a 1/200 dilution.

Performed heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human SIX6OS1 aa 200-300. The exact immunogen used to generate this antibody is proprietary information.

Q8N1H7

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100</p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

SIX6OS1 also referred to as Six6 opposite strand RNA 1 is a protein involved in various cellular processes. It has a molecular weight of approximately 91 kDa. Expression of SIX6OS1 occurs mostly in tissues like the testis and ovary highlighting its significance in reproductive biology. The protein plays an important part in the regulation of gene expression through interaction with other cellular proteins.
Biological function summary

SIX6OS1 participates in the formation of ribonucleoprotein complexes important for RNA processing and stability. It operates as part of a complex involved in transcriptional regulation influencing the expression of target genes essential for cell cycle progression and differentiation. By interacting with several proteins SIX6OS1 maintains cellular homeostasis and contributes to the integrity of gene expression networks necessary for proper cell function.

Pathways

SIX6OS1 plays a role in the Wnt signaling and cell cycle pathways. It interacts with associated proteins such as beta-catenin participating actively in signal transduction processes that influence gene expression. Through its involvement in these pathways SIX6OS1 ensures that cells respond appropriately to external and internal signals facilitating coordinated responses necessary for balanced cell proliferation and differentiation.

Alterations in SIX6OS1 expression are associated with specific conditions like gonadal dysgenesis and certain forms of infertility. Changes in the levels or activity of SIX6OS1 may disrupt normal gonadal function linked to the action of associated proteins like CREBBP. Variations in these proteins can result in impaired reproductive capability demonstrating the need to understand molecular interactions involving SIX6OS1 in the context of reproductive health.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Meiotic protein that localizes to the central element of the synaptonemal complex and is required for chromosome synapsis during meiotic recombination. Required for the appropriate processing of intermediate recombination nodules before crossover formation.
See full target information SIX6OS1
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB133633

Anti-Carcino Embryonic Antigen CEA antibody [EPCEAR7]

BOND RX™ Validated|KO Validated|RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Carcino Embryonic Antigen CEA antibody [EPCEAR7] (AB133633)

  • 0
  • 0
Primary Antibodies

AB122634

Anti-SYCE1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SYCE1 antibody (AB122634)

  • 0
  • 0
Primary Antibodies

AB97672

Anti-SCP3 antibody [Cor 10G11/7]

BOND RX™ Validated|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SCP3 antibody [Cor 10G11/7] (AB97672)

  • 5
  • 10
Primary Antibodies

AB243534

Anti-C3ORF62 antibody

Immunocytochemistry/ Immunofluorescence - Anti-C3ORF62 antibody (AB243534)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com