Rabbit Polyclonal SLC13A4/SUT1 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human SLC13A4 aa 100-300.
Images
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.03% Proclin 300
Constituents: PBS, 50% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human SLC13A4 aa 100-300. The exact immunogen used to generate this antibody is proprietary information. Database link Q9UKG4
Reactivity data
Select an application| WB | IHC-P | ICC/IF | |
|---|---|---|---|
| Human | Tested | Tested | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500.00000 - 1/5000.00000 | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/20.00000 - 1/200.00000 | Notes - |
ICC/IF
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/50.00000 - 1/200.00000 | Notes - |
Target data
Function
Sodium:sulfate symporter that mediates sulfate reabsorption in the high endothelial venules (HEV).
Alternative names
SUT1, SLC13A4, Solute carrier family 13 member 4, Na(+)/sulfate cotransporter SUT-1, NaS2
Recommended products
Rabbit Polyclonal SLC13A4/SUT1 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human SLC13A4 aa 100-300.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.03% Proclin 300
Constituents: PBS, 50% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human SLC13A4 aa 100-300. The exact immunogen used to generate this antibody is proprietary information. Database link Q9UKG4
- Purification technique
- Affinity purification Protein G
- Concentration
- Purification notes
Purity >95%
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
SLC13A4 also known as SUT1 is a protein that functions as a sodium-coupled transporter. It plays a role in the transport of sulfate ions across cellular membranes utilizing sodium gradients. SLC13A4 has a mass of approximately 68 kDa. It is expressed mainly in the placenta suggesting its importance in maternal-fetal transport processes. This protein also shows expression in other tissues albeit at lower levels.
- Biological function summary
This transporter is involved in sulfate homeostasis within the body. Sulfate is essential for synthesizing sulfated compounds which include glycosaminoglycans and proteoglycans. These are vital for various cellular functions including cell signaling and structural integrity. SLC13A4 does not operate as part of a larger protein complex. Instead it functions independently to ensure proper sulfate levels.
- Pathways
Transport processes involving SLC13A4 are key in metabolic and sulfur metabolism pathways. It is particularly involved in cellular uptake of sulfate essential for transferring sulfate from mother to fetus. SLC13A4 interacts with other membrane transport proteins such as SLC26A1 and SLC13A2 helping maintain the balance of sulfate within different tissues.
- Associated diseases and disorders
SLC13A4 disturbances can affect conditions such as placental insufficiency which impacts fetal development. Research also links its dysfunction to preeclampsia a pregnancy complication characterized by high blood pressure. Abnormal SLC13A4 activity affects sulfate availability disrupting the sulfation processes. Its interaction with proteins like SLC26A1 becomes particularly important because it compensates for imbalanced sulfate transport.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
4 product images
Western blot - Anti-SLC13A4/SUT1 antibody (ab236619)
All lanes: Western blot - Anti-SLC13A4/SUT1 antibody (ab236619) at 1/500 dilution
All lanes: HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
SecondaryAll lanes: Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 69 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC13A4/SUT1 antibody (ab236619)
Paraffin-embedded human placenta tissue stained for SLC13A4/SUT1 with ab236619 at a 1/100 dilution in immunohistochemical analysis.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC13A4/SUT1 antibody (ab236619)
Paraffin-embedded human testis tissue stained for SLC13A4/SUT1 with ab236619 at a 1/100 dilution in immunohistochemical analysis.
Immunocytochemistry/ Immunofluorescence - Anti-SLC13A4/SUT1 antibody (ab236619)
HEK-293 (Human epithelial cell line from embryonic kidney) cells stained for SLC13A4/SUT1 (Green) using ab236619 at a 1/100 dilution in ICC/IF. Secondary used is an Alexa-Fluor®488-conjugated Goat Anti-Rabbit IgG (H+L).
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com