AB133614

Anti-SLC25A38 antibody [EPBHMR1]

RabMAb
Recombinant
What is this?

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(5 Publications)

Rabbit Recombinant Monoclonal SLC25A38 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications.

View Alternative Names

Mitochondrial glycine transporter, Appoptosin, Mitochondrial glycine transporter GlyC, Solute carrier family 25 member 38, SLC25A38

1 Images

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Western blot - Anti-SLC25A38 antibody [EPBHMR1] (AB133614)

All lanes:

Western blot - Anti-SLC25A38 antibody [EPBHMR1] (ab133614) at 1/1000 dilution

All lanes:

TF-1 cell lysate at 10 µg

Secondary

All lanes:

HRP labelled goat anti-rabbit at 1/2000 dilution

Predicted band size: 33 kDa

Observed band size: 33 kDa

false

Carrier free

Anti-SLC25A38 antibody [EPBHMR1] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPBHMR1

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Product details

This antibody was developed as part of a collaboration between Epitomics, Sanford Burnham Medical Research Institute and the lab of Huaxi Xu.

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purity

Tissue culture supernatant

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Stable for 12 months at -20°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix. Required during erythropoiesis.. Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis.

See full target information SLC25A38

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 16:978 PubMed39856062

2025

SLC25A38 is required for mitochondrial pyridoxal 5'-phosphate (PLP) accumulation.

Applications

Unspecified application

Species

Unspecified reactive species

Izabella A Pena,Jeffrey S Shi,Sarah M Chang,Jason Yang,Samuel Block,Charles H Adelmann,Heather R Keys,Preston Ge,Shveta Bathla,Isabella H Witham,Grzegorz Sienski,Angus C Nairn,David M Sabatini,Caroline A Lewis,Nora Kory,Matthew G Vander Heiden,Myriam Heiman

Cell death & disease 13:330 PubMed35411037

2022

SLC25A38 as a novel biomarker for metastasis and clinical outcome in uveal melanoma.

Applications

Unspecified application

Species

Unspecified reactive species

Zhongyi Fan,Jingjing Duan,Pu Luo,Ling Shao,Qiong Chen,Xiaohua Tan,Lei Zhang,Xiaojie Xu

Frontiers in aging neuroscience 11:243 PubMed31551758

2019

Appoptosin Mediates Lesions Induced by Oxidative Stress Through the JNK-FoxO1 Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Cuilin Zhang,Zhenqiu Tan,Yongzhuang Xie,Yingjun Zhao,Timothy Y Huang,Zhaoping Lu,Hong Luo,Dan Can,Huaxi Xu,Yun-Wu Zhang,Xian Zhang

Journal of cell science 129:994-1002 PubMed26813789

2016

Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology.

Applications

Unspecified application

Species

Unspecified reactive species

Cuilin Zhang,Zhun Shi,Lingzhi Zhang,Zehua Zhou,Xiaoyuan Zheng,Guiying Liu,Guojun Bu,Paul E Fraser,Huaxi Xu,Yun-Wu Zhang

Neuron 87:963-75 PubMed26335643

2015

Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Yingjun Zhao,I-Chu Tseng,Charles J Heyser,Edward Rockenstein,Michael Mante,Anthony Adame,Qiuyang Zheng,Timothy Huang,Xin Wang,Pharhad E Arslan,Paramita Chakrabarty,Chengbiao Wu,Guojun Bu,William C Mobley,Yun-Wu Zhang,Peter St George-Hyslop,Eliezer Masliah,Paul Fraser,Huaxi Xu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-SLC25A38 antibody [EPBHMR1]

Western blot - Anti-SLC25A38 antibody [EPBHMR1] (AB133614)

Related conjugates and formulations (1)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (5)

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Product promise