Rabbit Polyclonal SLC26A8 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human SLC26A8 aa 600-900.
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Publications
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- Human mutation 43:2079-20902022Biallelic loss-of-function mutations in SEPTIN4 (C17ORF47), encoding a conserved annulus protein, cause thin midpiece spermatozoa and male infertility in humans.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGuanxiong Wang,Xiaoyu Zhu,Yang Gao,Mingrong Lv,Kuokuo Li,Dongdong Tang,Huan Wu,Chuan Xu,Hao Geng,Qunshan Shen,Xiaomin Zha,Zongliu Duan,Jingjing Zhang,Rong Hua,Fangbiao Tao,Ping Zhou,Zhaolian Wei,Yunxia Cao,Rui Guo,Xiaojin HePubMed 36135717
- Human mutation 43:434-4432021Novel biallelic mutations in SLC26A8 cause severe asthenozoospermia in humans owing to midpiece defects: Insights into a putative dominant genetic disease.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYang Gao,Huan Wu,Yuping Xu,Qunshan Shen,Chuan Xu,Hao Geng,Mingrong Lv,Qing Tan,Kuokuo Li,Dongdong Tang,Bing Song,Ping Zhou,Zhaolian Wei,Xiaojin He,Yunxia CaoPubMed 34923715
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 20% Glycerol (glycerin, glycerine), 1% BSA- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human SLC26A8 aa 600-900. The exact immunogen used to generate this antibody is proprietary information. Database link Q96RN1
Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Tested | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500.00000 - 1/3000.00000 | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
Target data
Function
Antiporter that mediates the exchange of sulfate and oxalate against chloride ions across a membrane (PubMed:11278976, PubMed:11834742). Stimulates anion transport activity of CFTR (PubMed:22121115, PubMed:23582645). May cooperate with CFTR in the regulation of chloride and bicarbonate ions fluxes required for activation of the ADCY10/PKA pathway during sperm motility and sperm capacitation (By similarity). May play a role in sperm tail differentiation and motility and hence male fertility (By similarity).
Alternative names
TAT1, SLC26A8, Testis anion transporter 1, Anion exchange transporter, Solute carrier family 26 member 8
Recommended products
Rabbit Polyclonal SLC26A8 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human SLC26A8 aa 600-900.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 20% Glycerol (glycerin, glycerine), 1% BSA- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human SLC26A8 aa 600-900. The exact immunogen used to generate this antibody is proprietary information. Database link Q96RN1
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
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2 product images
Western blot - Anti-SLC26A8 antibody (ab97782)
7.5% SDS-PAGE.
All lanes: Western blot - Anti-SLC26A8 antibody (ab97782) at 1/1000 dilution
All lanes: MOLT4 whole cell lysate at 30 µg
Predicted band size: 109 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC26A8 antibody (ab97782)
ab97782 at 1/500 dilution staining SLC26A8 in DLD1 xenograft by Immunohistochemistry, Paraffin-embedded tissue.
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