AB235166

Anti-Ferroportin antibody

Name: Anti-Ferroportin antibody (ab235166) | Abcam
Brand: Abcam Limited
SKU: AB235166
Price: 510 USD
Availability: InStock

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(7 Publications)

Rabbit Polyclonal SLC40A1 antibody. Suitable for WB and reacts with Human samples. Cited in 7 publications.

View Alternative Names

FPN, FPN1, IREG1, SLC11A3, MSTP079, SLC40A1, Ferroportin, Ferroportin-1, Iron-regulated transporter 1, Solute carrier family 40 member 1

1 Images

Supplier Data

Western blot - Anti-Ferroportin antibody (AB235166)

All lanes:

Western blot - Anti-Ferroportin antibody (ab235166) at 5 µg/mL

Lane 1:

CACO2 (Human colorectal adenocarcinoma cell line) whole cell lysate at 35 µg

Lane 2:

K562 (Human chronic myelogenous leukemia cell line from bone marrow ) whole cell lysate at 35 µg

Lane 3:

HepG2 (Human liver hepatocellular carcinoma cell line) whole cell lysate at 35 µg

Lane 4:

MCF7 (Human breast adenocarcinoma cell line) whole cell lysate at 35 µg

Secondary

All lanes:

Goat anti-Rabbit IgG [H&L] HRP at 1/70000 dilution

Predicted band size: 63 kDa

false

Exposure time: 40s

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "5 µg/mL", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification

Storage buffer

Preservative: 0.01% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Transports Fe(2+) from the inside of a cell to the outside of the cell, playing a key role for maintaining systemic iron homeostasis (PubMed : 15692071, PubMed : 22178646, PubMed : 22682227, PubMed : 24304836, PubMed : 29237594, PubMed : 29599243, PubMed : 30247984). Transports iron from intestinal, splenic, hepatic cells, macrophages and erythrocytes into the blood to provide iron to other tissues (By similarity). Controls therefore dietary iron uptake, iron recycling by macrophages and erythrocytes, and release of iron stores in hepatocytes (By similarity). When iron is in excess in serum, circulating HAMP/hepcidin levels increase resulting in a degradation of SLC40A1, thus limiting the iron efflux to plasma (PubMed : 22682227, PubMed : 29237594, PubMed : 32814342).

See full target information Ferroportin

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Publications (7)

Recent publications for all applications. Explore the full list and refine your search

Physiological reports 13:e70580 PubMed40999314

2025

High-intensity interval training attenuates cardiac injury by targeting ferroptosis and endoplasmic reticulum-stress in male rats with heart failure.

Applications

Unspecified application

Species

Unspecified reactive species

Aida Sabouri,Abbasali Gaeini,Soheila Adeli,Alireza Ghardashi Afousi

Oncology letters 28:298 PubMed38751752

2024

Mechanism of targeting the mTOR pathway to regulate ferroptosis in NSCLC with different EGFR mutations.

Applications

Unspecified application

Species

Unspecified reactive species

Chunjiao Wu,Rui Zhong,Tianxue Wei,Yulong Jin,Chunying He,Hui Li,Ying Cheng

Frontiers in cell and developmental biology 11:1272667 PubMed38033861

2023

Iron affects the sphere-forming ability of ovarian cancer cells in non-adherent culture conditions.

Applications

Unspecified application

Species

Unspecified reactive species

Anna Martina Battaglia,Alessandro Sacco,Eleonora Vecchio,Stefania Scicchitano,Lavinia Petriaggi,Emanuele Giorgio,Stefania Bulotta,Sonia Levi,Concetta Maria Faniello,Flavia Biamonte,Francesco Costanzo

Nanomaterials (Basel, Switzerland) 12: PubMed36432281

2022

Bacterial Magnetosomes Release Iron Ions and Induce Regulation of Iron Homeostasis in Endothelial Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Wenjia Lai,Dan Li,Qingsong Wang,Yan Ma,Jiesheng Tian,Qiaojun Fang

Evidence-based complementary and alternative medicine : eCAM 2022:6177477 PubMed36276874

2022

Simvastatin Inhibits Endometrial Cancer Malignant Behaviors by Suppressing RAS/Mitogen-Activated Protein Kinase (MAPK) Pathway-Mediated Reactive Oxygen Species (ROS) and Ferroptosis.

Applications

Unspecified application

Species

Unspecified reactive species

Dan Zhou,Qiuhua Wu,Huajuan Qiu,Mi Li,Yanqin Ji

Frontiers in pharmacology 13:973611 PubMed36105203

2022

S-3'-hydroxy-7', 2', 4'-trimethoxyisoxane, a novel ferroptosis inducer, promotes NSCLC cell death through inhibiting Nrf2/HO-1 signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jing Chen,Songlin Zhou,Xian Zhang,Huange Zhao

Cell death and differentiation 30:69-81 PubMed35933500

2022

Pathologically high intraocular pressure disturbs normal iron homeostasis and leads to retinal ganglion cell ferroptosis in glaucoma.

Applications

Unspecified application

Species

Unspecified reactive species

Fei Yao,Jingjie Peng,Endong Zhang,Dan Ji,Zhaolin Gao,Yixiong Tang,Xueyan Yao,Xiaobo Xia

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Ferroportin antibody

Western blot - Anti-Ferroportin antibody (AB235166)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (7)

Product promise