JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB239511

Anti-Ferroportin antibody [C8]

Be the first to review this product! Submit a review

|

(14 Publications)

Mouse Monoclonal SLC40A1 antibody. Suitable for WB and reacts with Human samples. Cited in 14 publications. Immunogen corresponding to Recombinant Fragment Protein within Human Ferroportin aa 100-350.

View Alternative Names

FPN, FPN1, IREG1, SLC11A3, MSTP079, SLC40A1, Ferroportin, Ferroportin-1, Iron-regulated transporter 1, Solute carrier family 40 member 1

1 Images
Western blot - Anti-Ferroportin antibody [C8] (AB239511)
  • WB

Supplier Data

Western blot - Anti-Ferroportin antibody [C8] (AB239511)

All lanes:

Western blot - Anti-Ferroportin antibody [C8] (ab239511) at 5 µg/mL

All lanes:

Recombinant human SLC40A1 protein

Predicted band size: 63 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

C8

Isotype

IgG2b

Light chain type

kappa

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human Ferroportin aa 100-350. The exact immunogen used to generate this antibody is proprietary information.

Q9NP59

style
left-column

Alternative Products

Primary Antibodies

AB235166

Anti-Ferroportin antibody

Western blot - Anti-Ferroportin antibody (AB235166)

  • 0
  • 0
Primary Antibodies

AB239583

Anti-Ferroportin antibody [C2]

Western blot - Anti-Ferroportin antibody [C2] (AB239583)

  • 0
  • 0
Primary Antibodies

AB78066

Anti-Ferroportin antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ferroportin antibody (AB78066)

  • 5
  • 3

Complementary Products

Assay Kits

AB83366

Iron Assay Kit (Colorimetric)

Biochemical assay - Iron Assay Kit (Colorimetric) (AB83366)

  • 4
  • 3
Primary Antibodies

AB125066

Anti-Glutathione Peroxidase 4 antibody [EPNCIR144]

BOND RX™ Validated|KO Validated|RabMAb|Recombinant|Lab Essentials

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Glutathione Peroxidase 4 antibody [EPNCIR144] (AB125066)

  • 5
  • 13
Primary Antibodies

AB214039

Anti-Transferrin Receptor antibody [EPR20584]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Transferrin Receptor antibody [EPR20584] (AB214039)

  • 5
  • 1
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB75973

Anti-Ferritin heavy chain antibody [EPR3004Y]

20ul selling size|RabMAb|Recombinant|KO Validated

Western blot - Anti-Ferritin heavy chain antibody [EPR3004Y] (AB75973)

  • 4
  • 7
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "notRecommended", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A/G
Purification notes
Purified from TCS.
Storage buffer
pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Transports Fe(2+) from the inside of a cell to the outside of the cell, playing a key role for maintaining systemic iron homeostasis (PubMed : 15692071, PubMed : 22178646, PubMed : 22682227, PubMed : 24304836, PubMed : 29237594, PubMed : 29599243, PubMed : 30247984). Transports iron from intestinal, splenic, hepatic cells, macrophages and erythrocytes into the blood to provide iron to other tissues (By similarity). Controls therefore dietary iron uptake, iron recycling by macrophages and erythrocytes, and release of iron stores in hepatocytes (By similarity). When iron is in excess in serum, circulating HAMP/hepcidin levels increase resulting in a degradation of SLC40A1, thus limiting the iron efflux to plasma (PubMed : 22682227, PubMed : 29237594, PubMed : 32814342).
See full target information Ferroportin
style
left-column

Publications (14)

Recent publications for all applications. Explore the full list and refine your search

American journal of cancer research 15:3434-3448 PubMed40948531

2025

Differentiating early-stage nasopharyngeal carcinoma from adenoidal hypertrophy via SLC40A1 expression and developing a prognostic model for disease progression.

Applications

Unspecified application

Species

Unspecified reactive species

Hongwei Wang,Suqing Qi,Chaobing Liu,Zhenhua Qiao,Chao Zhang

World journal of gastrointestinal oncology 17:104522 PubMed40487942

2025

Simvastatin inhibits proliferation and migration, promotes oxidative stress and ferroptosis in colon cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Ying Liu,Hao Ge,Zhi-Min Fan,Ting Lu,Lei He,Meng Li,Hao-Ran Zhao,Qiang Leng

Journal of molecular neuroscience : MN 75:63 PubMed40317390

2025

Electroacupuncture Inhibits Ferroptosis by Modulating Iron Metabolism and Oxidative Stress to Alleviate Cerebral Ischemia-Reperfusion Injury.

Applications

Unspecified application

Species

Unspecified reactive species

Yaoyao Liu,Qi Wang,Ziwen Hou,Ying Gao,Peng Li

Molecular medicine reports 31: PubMed40183404

2025

α‑ketoglutarate protects against septic cardiomyopathy by improving mitochondrial mitophagy and fission.

Applications

Unspecified application

Species

Unspecified reactive species

Wei Wu,Qiong Ma,Bo-Tao Li,Shuang Shi,Gong-Chang Guan,Jun-Kui Wang,Bao-Yao Xue,Zhong-Wei Liu

Frontiers in pharmacology 15:1503064 PubMed39619616

2024

Tetramethylpyrazine inhibits ferroptosis in spinal cord injury by regulating iron metabolism through the NRF2/ARE pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jingwei Tao,Jingya Zhou,Hanjie Zhu,Lin Xu,Jizhou Yang,Xiaohong Mu,Xiao Fan

Heliyon 10:e33675 PubMed39071725

2024

Acupuncture improve proteinuria in diabetic kidney disease rats by inhibiting ferroptosis and epithelial-mesenchymal transition.

Applications

Unspecified application

Species

Unspecified reactive species

J I Yue,Z H A N G Xin-Yuan,X I A O Yun-Ming,Z H U A N G Zi-Hao,Y A N G Xiao-Hui,L I Xin-Ju

Environmental science and pollution research international 30:111051-111061 PubMed37801247

2023

PM 2.5 juvenile exposure-induced spermatogenesis dysfunction by triggering testes ferroptosis and antioxidative vitamins intervention in adult male rats.

Applications

Unspecified application

Species

Unspecified reactive species

Xiang Liu,Yaya Ai,Mingchen Xiao,Cao Wang,Zhen Shu,Jia Yin,Yu Chu,Qing Xiao,Bin Liu

Redox biology 62:102708 PubMed37116254

2023

17β-oestradiol inhibits ferroptosis in the hippocampus by upregulating DHODH and further improves memory decline after ovariectomy.

Applications

Unspecified application

Species

Unspecified reactive species

Ying Tian,Yuan Xie,Zaixin Guo,Penghui Feng,Yang You,Qi Yu

Neurochemical research 48:2542-2551 PubMed37061657

2023

Dithiolethiones D3T and ACDT Protect Against Iron Overload-Induced Cytotoxicity and Serve as Ferroptosis Inhibitors in U-87 MG Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Neha Kulkarni,Rajitha Gadde,Swati Betharia

Cancer cell international 23:5 PubMed36639654

2023

Heat shock protein 27 deficiency promotes ferrous ion absorption and enhances acyl-Coenzyme A synthetase long-chain family member 4 stability to promote glioblastoma cell ferroptosis.

Applications

Unspecified application

Species

Unspecified reactive species

Kai Zhang,Yue Wu,Guangliang Chen,Hao Wang,Yongsheng Liu,Youxin Zhou
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com