AB203827

Anti-SLC45A3 antibody [EPR18068]

RabMAb
Recombinant
What is this?

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(1 Publication)

Rabbit Recombinant Monoclonal SLC45A3 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication.

View Alternative Names

PCANAP6, PRST, SLC45A3, Solute carrier family 45 member 3, Prostate cancer-associated protein 6, Prostein

4 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC45A3 antibody [EPR18068] (AB203827)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC45A3 antibody [EPR18068] (AB203827)

Immunohistochemical analysis of paraffin-embedded Human kidney tissue labeling SLC45A3 with ab203827 at 1/2000 dilution followed by Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/500 dilution. No staining on Human kidney tissue is observed. Counter stained with Hematoxylin.

Secondary antibody only control : Used PBS instead of primary antibody secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/500 dilution.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC45A3 antibody [EPR18068] (AB203827)

Immunohistochemical analysis of paraffin-embedded Human prostatic carcinoma tissue labeling SLC45A3 with ab203827 at 1/2000 dilution followed by Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/500 dilution. Cytoplasmic staining on Human prostatic carcinoma tissue is observed. Counter stained with Hematoxylin.

Secondary antibody only control : Used PBS instead of primary antibody secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/500 dilution.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC45A3 antibody [EPR18068] (AB203827)

Immunohistochemical analysis of paraffin-embedded Human cerebral cortex tissue labeling SLC45A3 with ab203827 at 1/2000 dilution followed by Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/500 dilution. No staining on Human cerebral cortex tissue is observed. Counter stained with Hematoxylin.

Secondary antibody only control : Used PBS instead of primary antibody secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/500 dilution.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC45A3 antibody [EPR18068] (AB203827)

Immunohistochemical analysis of paraffin-embedded Human prostatic hyperplasia tissue labeling SLC45A3 with ab203827 at 1/2000 dilution followed by Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/500 dilution. Cytoplasmic staining on Human prostatic hyperplasia tissue is observed. Counter stained with Hematoxylin.

Secondary antibody only control : Used PBS instead of primary antibody secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/500 dilution.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Carrier free

Anti-SLC45A3 antibody [EPR18068] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR18068

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/2000", "IHCP-species-notes": "<p></p>" } } }

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Product details

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Conditional Ambient

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

SLC45A3 also known as Prostate Cancer Associated Transcript 6 (PCAT6) is a member of the solute carrier family that functions primarily as a transporter. This protein has a mass of approximately 51 kDa. It is primarily expressed in the prostate but also found in other tissues though at lower levels. SLC45A3 is involved in transporting certain solutes which is important for maintaining cellular homeostasis.

Biological function summary

This transporter plays a critical role in regulating pH and solute concentration within the cells. SLC45A3 does not appear to belong to a large protein complex but it interacts with elements of the intracellular environment that modulate its activity. Its solute transportation role affects a range of cellular processes impacting overall cell health and function.

Pathways

SLC45A3 operates within the cellular homeostasis and metabolic pathways. It closely relates to the acid-base balance pathway ensuring that cells maintain optimal internal conditions. Additionally its function can link to the androgen receptor signaling pathway an important pathway in prostate tissue where it may interact indirectly with other transport proteins that assist in maintaining homeostatic balance.

SLC45A3 is significantly connected to prostate cancer and may also have implications in other types of cancer. It associates with the androgen receptor which plays a major role in the progression of prostate cancer. Understanding the dynamics of SLC45A3 can help in comprehending its role in these diseases potentially offering targets for new therapeutic strategies.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Proton-associated sucrose transporter. May be able to transport also glucose and fructose.

See full target information SLC45A3

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 16:6032 PubMed40595652

2025

EZH2 loss promotes gastric squamous cell carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Mengsha Zhang,Ailing Zhong,Hongyu Liu,Lei Zhao,Yingjie Wang,Zhenghao Lu,Lanxin Zhang,Xiangyu Pan,Zuoyu Liang,Limin Gao,Xuelan Chen,Jian Wang,Siqi Dai,Xudong Wan,Manli Wang,Jingyao Chen,Jiajia Du,Shuang Chen,Tingfa Peng,Jingyang Cai,Liuxiang Chen,Yang Yang,Chaoxin Xiao,Menglin Yao,Jing Xu,Runkuan Qin,Chan Yang,Baohong Wu,Qi Zhang,Shengzhuo Liu,Chengjian Zhao,Hongxin Deng,Yuan Wang,Lu Chen,Jiankun Hu,Bing Hu,Shengyong Yang,Feifei Na,Linjie Guo,Yu Liu,Chong Chen

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-SLC45A3 antibody [EPR18068]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC45A3 antibody [EPR18068] (AB203827)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC45A3 antibody [EPR18068] (AB203827)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC45A3 antibody [EPR18068] (AB203827)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC45A3 antibody [EPR18068] (AB203827)

Related conjugates and formulations (1)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Primary Antibodies

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Primary Antibodies

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

Product promise