AB236898

Anti-Slc6a6/Taut antibody

Name: Anti-Slc6a6/Taut antibody (ab236898) | Abcam
Brand: Abcam Limited
SKU: AB236898
Rating: 4 (1 reviews)

(1 Review)

(7 Publications)

Anti-Slc6a6/Taut antibody (ab236898) is a rabbit polyclonal antibody detecting Slc6a6/Taut in Western Blot, ICC/IF. Suitable for Human.

View Alternative Names

Sodium- and chloride-dependent taurine transporter, Solute carrier family 6 member 6, Taurine transporter, TauT, SLC6A6

1 Images

Immunocytochemistry/ Immunofluorescence - Anti-Slc6a6/Taut antibody (AB236898)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-Slc6a6/Taut antibody (AB236898)

HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for Slc6a6/Taut (green) using ab236898 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488^® conjugated Goat Anti-Rabbit IgG (H+L).

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

ICC/IF, WB

applications

Immunogen

Recombinant Fragment Protein within Human SLC6A6 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

P31641

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Product details

What is this antibody validated in?
Anti-Slc6a6/Taut antibody (ab236898) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples.

What is the molecular weight of Slc6a6/Taut?
Anti-Slc6a6/Taut (ab236898) specifically detects a band for Slc6a6/Taut (UniProt: P31641) at a molecular weight of 70kDa.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Purification notes

Purity >95%.

Storage buffer

pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Mediates sodium- and chloride-dependent transport of taurine (PubMed : 31345061, PubMed : 31903486, PubMed : 8010975, PubMed : 8382624, PubMed : 8654117, PubMed : 40108165, PubMed : 39837997). Mediates transport of beta-alanine (PubMed : 8010975, PubMed : 40108165, PubMed : 39837997). Can also mediate transport of hypotaurine and gamma-aminobutyric acid (GABA) (By similarity).

See full target information SLC6A6

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Publications (7)

Recent publications for all applications. Explore the full list and refine your search

Genome medicine 17:56 PubMed40390022

2025

Spatiotemporal single-cell analysis elucidates the cellular and molecular dynamics of human cornea aging.

Applications

Unspecified application

Species

Unspecified reactive species

Dan Jiang,Ke Li,Yining Sun,Zicheng Zhang,Shuang Xie,Xintong Yu,Ruoqi Wang,Ying Feng,Qinxiang Zheng,Yajing Wen,Peter S Reinach,Yuanyuan Du,Meng Zhou,Wei Chen

Nutrients 16: PubMed38931171

2024

Modeling of Intracellular Taurine Levels Associated with Ovarian Cancer Reveals Activation of p53, ERK, mTOR and DNA-Damage-Sensing-Dependent Cell Protection.

Applications

Unspecified application

Species

Unspecified reactive species

Daniel Centeno,Sadaf Farsinejad,Elena Kochetkova,Tatiana Volpari,Aleksandra Gladych-Macioszek,Agnieszka Klupczynska-Gabryszak,Teagan Polotaye,Michael Greenberg,Douglas Kung,Emily Hyde,Sarah Alshehri,Tonja Pavlovic,William Sullivan,Szymon Plewa,Helin Vakifahmetoglu-Norberg,Frederick J Monsma,Patricia A J Muller,Jan Matysiak,Mikołaj Piotr Zaborowski,Analisa DiFeo,Erik Norberg,Laura A Martin,Marcin Iwanicki

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37:e23134 PubMed37561545

2023

Deficiency of Pdk1 drives heart failure by impairing taurine homeostasis through Slc6a6.

Applications

Unspecified application

Species

Unspecified reactive species

Chen Li,Yi Zhou,Yan Niu,Wenting He,Xinyi Wang,Xi Zhang,Yali Wu,Wenli Zhang,Liangcai Zhao,Hong Zheng,Weihong Song,Hongchang Gao

International journal of molecular sciences 24: PubMed36769341

2023

Ant-Neointimal Formation Effects of SLC6A6 in Preventing Vascular Smooth Muscle Cell Proliferation and Migration via Wnt/β-Catenin Signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Zhihua Rong,Fengshi Li,Rui Zhang,Shuai Niu,Xiao Di,Leng Ni,Changwei Liu

Human reproduction (Oxford, England) 37:1229-1243 PubMed35526154

2022

Taurine and its transporter TAUT positively affect male reproduction and early embryo development.

Applications

Unspecified application

Species

Unspecified reactive species

Hua Wu,Xinyue Zhang,Jihong Yang,Ting Feng,Yao Chen,Ruizhi Feng,Hui Wang,Yun Qian

Frontiers in bioengineering and biotechnology 8:456 PubMed32500067

2020

Optimisation of a Novel Bio-Substrate as a Treatment for Atrophic Age-Related Macular Degeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Rachel McCormick,Ian Pearce,Stephen Kaye,Atikah Haneef

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 33:11507-11527 PubMed31345061

2019

Biallelic mutation of human encoding the taurine transporter TAUT is linked to early retinal degeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Markus N Preising,Boris Görg,Christoph Friedburg,Natalia Qvartskhava,Birgit S Budde,Michele Bonus,Mohammad R Toliat,Christopher Pfleger,Janine Altmüller,Diran Herebian,Mila Beyer,Helge J Zöllner,Hans-Jörg Wittsack,Jörg Schaper,Dirk Klee,Ulrich Zechner,Peter Nürnberg,Jörg Schipper,Alfons Schnitzler,Holger Gohlke,Birgit Lorenz,Dieter Häussinger,Hanno J Bolz

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Slc6a6/Taut antibody

Immunocytochemistry/ Immunofluorescence - Anti-Slc6a6/Taut antibody (AB236898)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Primary Antibodies

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (7)

Product promise